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anti-ATP2B2 antibody :: Rabbit anti-Human, Rat ATP2B2 Polyclonal Antibody

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Catalog # MBS9610074
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ATP2B2, Polyclonal Antibody

Popular Item
Also Known As

ATP2B2 Antibody

Product Synonym Names
AT2B2_HUMAN; atp2b2; ATPase plasma membrane Ca2+ transporting 2; Plasma membrane calcium ATPase 2; Plasma membrane calcium ATPase; Plasma membrane calcium ATPase isoform 2; Plasma membrane calcium pump isoform 2; Plasma membrane calcium transporting ATPase 2; Plasma membrane calcium-transporting ATPase 2; PMCA2; PMCA2a; PMCA2i
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1243
3D Structure
ModBase 3D Structure for Q01814
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Specificity
ATP2B2 antibody detects endogenous levels of total ATP2B2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human ATP2B2
Subcellular Location
Cell Membrane
Tissue Specificity
Mainly expressed in brain cortex. Found in low levels in skeletal muscle, heart muscle, stomach, liver, kidney and lung. Isoforms containing segment B are found in brain cortex and at low levels in other tissues. Isoforms containing segments X and W are found at low levels in all tissues. Isoforms containing segment A and segment Z are found at low levels in skeletal muscle and heart muscle.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-ATP2B2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ATP2B2 antibody
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Subunit Structure: Interacts with PDZD11.
Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
Applications Tested/Suitable for anti-ATP2B2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ATP2B2 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-ATP2B2 antibody
Western blot analysis of ATP2B2 using COLO205 whole cell lysates
anti-ATP2B2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ATP2B2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 137 kDa
Predicted: 137 kDa
NCBI Official Full Name
plasma membrane calcium-transporting ATPase 2 isoform 1
NCBI Official Synonym Full Names
ATPase plasma membrane Ca2+ transporting 2
NCBI Official Symbol
ATP2B2  [Similar Products]
NCBI Official Synonym Symbols
PMCA2; PMCA2a; PMCA2i
  [Similar Products]
NCBI Protein Information
plasma membrane calcium-transporting ATPase 2
UniProt Protein Name
Plasma membrane calcium-transporting ATPase 2
UniProt Synonym Protein Names
Plasma membrane calcium ATPase isoform 2; Plasma membrane calcium pump isoform 2
UniProt Gene Name
ATP2B2  [Similar Products]
UniProt Synonym Gene Names
PMCA2; PMCA2  [Similar Products]
NCBI Summary for ATP2B2
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for ATP2B2
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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