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anti-DGKK antibody :: anti-Human, Rat DGK kappa Polyclonal Antibody

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Catalog # MBS8242534
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

DGK kappa (DGKK), Polyclonal Antibody

Popular Item
Also Known As

Anti-DGK kappa Antibody

Product Synonym Names
Diacylglycerol kinase kappa; DAG kinase kappa; 142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappa
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1271
OMIM
300837
3D Structure
ModBase 3D Structure for Q5KSL6
Clonality
Polyclonal
Species Reactivity
Human, Rat
Specificity
Recognizes endogenous levels of DGK kappa protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Source
Rabbit
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DGK kappa. The exact sequence is proprietary.
Preparation and Storage
Shipped and store at 4°C. Upon delivery aliquot and store at -20°C for one year.
Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-DGKK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DGKK antibody
Rabbit polyclonal antibody to DGK kappa
Applications Tested/Suitable for anti-DGKK antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-DGKK antibody
Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200); Immunofluorescence/Immunocytochemistry: (1/100 - 1/500)

Western Blot (WB) of anti-DGKK antibody
Western blot analysis of DGK kappa expression in human lung (A), rat kidney (B) whole cell lysates.
anti-DGKK antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-DGKK antibody
Immunohistochemical analysis of DGK kappa staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-DGKK antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for DGKK. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
141,829 Da
NCBI Official Full Name
Diacylglycerol kinase kappa
NCBI Official Synonym Full Names
diacylglycerol kinase kappa
NCBI Official Symbol
NCBI Protein Information
diacylglycerol kinase kappa
UniProt Protein Name
Diacylglycerol kinase kappa
UniProt Synonym Protein Names
142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappa
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
DAG kinase kappa; DGK-kappa  [Similar Products]
UniProt Entry Name
DGKK_HUMAN
NCBI Summary for DGKK
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]
UniProt Comments for DGKK
DGKK: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Belongs to the eukaryotic diacylglycerol kinase family.

Protein type: EC 2.7.1.107; Kinase, lipid

Chromosomal Location of Human Ortholog: Xp11.22

Cellular Component: cytoplasm; plasma membrane

Molecular Function: ATP binding; diacylglycerol kinase activity; metal ion binding

Biological Process: blood coagulation; diacylglycerol metabolic process; phosphorylation; platelet activation; protein kinase C activation; response to oxidative stress
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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