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anti-Drd1a antibody :: Rabbit anti-Human, Rat Dopamine Receptor D(1A) Polyclonal Antibody

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Catalog # MBS622982
Unit / Price
  0.1 mg  /  $610 +1 FREE 8GB USB
anti-Drd1a antibody
Product Name

Dopamine Receptor D(1A) (Drd1a), Polyclonal Antibody

Full Product Name

Dopamine Receptor D(1A) (DRD1A, D(1A) Dopamine Receptor, DADR, Dopamine D1 Receptor, Dopamine Receptor D1, DRD1)

Product Synonym Names
Anti -Dopamine Receptor D(1A) (DRD1A, D(1A) Dopamine Receptor, DADR, Dopamine D1 Receptor, Dopamine Receptor D1, DRD1)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 17; NC_005116.2 (16655926..16658161). Location: 17p14
3D Structure
ModBase 3D Structure for P18901
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Specificity
Recognizes human D(1A) dopamine receptor at 49kD. Species Crossreactivity
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Form/Format
Supplied as a lyophilized powder PBS, 5% BSA, 0.05% Thimerosal, 0.05% sodium azide. Reconstitute with 100ul sterile dH2O.
Immunogen
Synthetic peptide corresponding to aa425-437, DYDTDVSLEKIQP to human D(1A) dopamine receptor.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-Drd1a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Drd1a antibody
D(1A) dopamine receptor (DRD1) is a multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. DRD1 is one of five receptors for dopamine. DRD1 stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. At least 2 isoforms exist arising from alternate transcription initiation sites.
Product Categories/Family for anti-Drd1a antibody
Applications Tested/Suitable for anti-Drd1a antibody
Western Blot (WB)
Application Notes for anti-Drd1a antibody
Suitable for use in Western Blot.
Dilution: Western Blot: 1ug/ml
NCBI/Uniprot data below describe general gene information for Drd1a. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,428 Da[Similar Products]
NCBI Official Full Name
D(1A) dopamine receptor
NCBI Official Synonym Full Names
dopamine receptor D1A
NCBI Official Symbol
Drd1a  [Similar Products]
NCBI Official Synonym Symbols
D1a; Drd1; Drd-1
  [Similar Products]
NCBI Protein Information
D(1A) dopamine receptor; D(1A) dopamine receptor; Dopamine-1A receptor; dopamine D1 receptor; dopamine receptor 1A
UniProt Protein Name
D(1A) dopamine receptor
UniProt Synonym Protein Names
Dopamine D1 receptor
UniProt Gene Name
UniProt Synonym Gene Names
Drd1a  [Similar Products]
UniProt Entry Name
DRD1_RAT
NCBI Summary for Drd1a
induces dopamine sensitive adenylate cyclase activation; plays a role in regulating food intake [RGD]
UniProt Comments for Drd1a
DRD1: a G-protein coupled receptor.One of the five types (D1 to D5) of receptors for dopamine. The most abundant dopamine receptor in the central nervous system. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Interacts with calcyon.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; cell; integral to plasma membrane; dendrite; dendritic spine; integral to membrane; caveola; cell soma; membrane; axon; plasma membrane; intracellular; nerve terminal; dendritic shaft; nucleus

Molecular Function: angiotensin receptor binding; G-protein coupled receptor activity; protein binding; dopamine receptor activity; protein heterodimerization activity; dopamine binding; protein complex binding; G-protein alpha-subunit binding; drug binding; dopamine D1 receptor-like receptor activity; D3 dopamine receptor binding; protein phosphatase binding; ATPase binding; receptor binding

Biological Process: response to nicotine; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); prepulse inhibition; thermoregulation; response to organic cyclic substance; G-protein signaling, adenylate cyclase activating pathway; adult walking behavior; protein import into nucleus; conditioned taste aversion; positive regulation of cAMP biosynthetic process; positive regulation of adenylate cyclase activity; phosphatidylinositol metabolic process; response to food; response to drug; phosphatidylinositol catabolic process; dopamine transport; dentate gyrus development; cerebral cortex GABAergic interneuron migration; adenylate cyclase activation; mating behavior; transmission of nerve impulse; social behavior; response to amino acid stimulus; response to organic nitrogen; G-protein signaling, coupled to cyclic nucleotide second messenger; response to ethanol; cellular response to insulin stimulus; response to steroid hormone stimulus; regulation of vasoconstriction; glucose import; operant conditioning; dopamine receptor signaling pathway; negative regulation of protein kinase activity; response to activity; positive regulation of membrane potential; regulation of ion transport; regulation of long-term neuronal synaptic plasticity; synaptic transmission, dopaminergic; peristalsis; startle response; behavioral fear response; negative regulation of circadian sleep/wake cycle, sleep; generation of action potential; response to morphine; locomotory behavior; orbitofrontal cortex development; vasodilation; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; intracellular protein transport; synaptic transmission; synaptogenesis; muscle contraction; behavioral response to cocaine; visual learning; feeding behavior; negative regulation of cell migration; associative learning; dopamine receptor, adenylate cyclase activating pathway; grooming behavior; response to retinoic acid; striatum development; maternal behavior; regulation of dopamine metabolic process; response to amphetamine; hippocampus development; calcium-mediated signaling; learning; response to cocaine; astrocyte development; memory; G-protein coupled receptor protein signaling pathway; habituation; sensitization; positive regulation of release of sequestered calcium ion into cytosol; dopamine receptor, phospholipase C activating pathway; positive regulation of cell migration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-Drd1a antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >19 publications with Drd1a and Brain
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