• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-MTO1 antibody :: Rabbit anti-Human, Rat MTO1 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS7043783
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

MTO1, Polyclonal Antibody

Popular Item
Full Product Name

MTO1 Antibody

Product Synonym Names
Protein MTO1 homolog, mitochondrial; MTO1; CGI-02
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
614667
3D Structure
ModBase 3D Structure for Q9Y2Z2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Protein MTO1 homolog, mitochondrial protein (420-680AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161114 / sc-161115
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-MTO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MTO1 antibody
Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
Applications Tested/Suitable for anti-MTO1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-MTO1 antibody
Western blot
All lanes: MTO1 antibody at 2.25 ug/ml
Lane 1: Rat heart tissue
Lane 2: Jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 80,67,35,78,73,82 kDa
Observed band size: 80,65,36 kDa

anti-MTO1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-MTO1 antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7043783 at dilution of 1:100
anti-MTO1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-MTO1 antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7043783 at dilution of 1:100
anti-MTO1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for MTO1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
81,538 Da
NCBI Official Full Name
protein MTO1 homolog, mitochondrial isoform c
NCBI Official Synonym Full Names
mitochondrial tRNA translation optimization 1
NCBI Official Symbol
NCBI Official Synonym Symbols
CGI-02; COXPD10
  [Similar Products]
NCBI Protein Information
protein MTO1 homolog, mitochondrial
UniProt Protein Name
Protein MTO1 homolog, mitochondrial
UniProt Gene Name
UniProt Entry Name
MTO1_HUMAN
NCBI Summary for MTO1
This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for MTO1
MTO1: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. Defects in MTO1 are the cause of combined oxidative phosphorylation deficiency type 10 (COXPD10). An autosomal recessive disorder resulting in variable defects of mitochondrial oxidative respiration. Affected individuals present in infancy with hypertrophic cardiomyopathy and lactic acidosis. The severity is variable, but can be fatal in the most severe cases. Belongs to the MnmG family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA processing

Chromosomal Location of Human Ortholog: 6q13

Disease: Combined Oxidative Phosphorylation Deficiency 10
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000