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anti-PTPN18 antibody :: Rabbit anti-Human, Rat PTPN18 Polyclonal Antibody

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Catalog # MBS7046295
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

PTPN18, Polyclonal Antibody

Popular Item
Full Product Name

PTPN18 Antibody

Product Synonym Names
Tyrosine-protein phosphatase non-receptor type 18; Brain-derived phosphatase; PTPN18; BDP1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
606587
3D Structure
ModBase 3D Structure for Q99952
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Tyrosine-protein phosphatase non-receptor type 18 protein (N-210AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8227
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PTPN18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PTPN18 antibody
Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
Applications Tested/Suitable for anti-PTPN18 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-PTPN18 antibody
Western blot
All lanes: PTPN18 antibody IgG at 2.98ug/ml+ Rat heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 51,39 kDa
Observed band size: 50 kDa

anti-PTPN18 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PTPN18 antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7046295 at dilution 1:100
anti-PTPN18 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PTPN18. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,476 Da
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 18 isoform 2
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 18
NCBI Official Symbol
PTPN18  [Similar Products]
NCBI Official Synonym Symbols
BDP1; PTP-HSCF
  [Similar Products]
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 18
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 18
UniProt Synonym Protein Names
Brain-derived phosphatase
UniProt Gene Name
PTPN18  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
PTN18_HUMAN
NCBI Summary for PTPN18
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
UniProt Comments for PTPN18
BDP1: a member of the non-receptor protein tyrosine phosphatase (PTP) family. Contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This gene was found to be expressed in brain, colon tissues, and several different tumor-derived cell lines.

Protein type: EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 2q21.1

Molecular Function: protein binding

Biological Process: protein amino acid dephosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-PTPN18 antibody
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