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anti-Stat2 antibody :: Rabbit anti-Human, Rat Stat2 Polyclonal Antibody

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Catalog # MBS2534716
Unit / Price
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  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Stat2, Polyclonal Antibody

Full Product Name

Phospho-Stat2 (Y690) Polyclonal Antibody

Product Synonym Names
STAT2; Signal transducer and activator of transcription 2; p113
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600556
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Purity/Purification
Antigen Affinity Purified
Concentration
1mg/ml (lot specific)
Immunogen
Synthesized peptide derived from human Stat2 around the phosphorylation site of Y690.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-Stat2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-Stat2 antibody
Applications Tested/Suitable for anti-Stat2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-Stat2 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-Stat2 antibody
Western Blot analysis of various cells with Phospho-Stat2 (Tyr690) Polyclonal Antibody
anti-Stat2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for Stat2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW: 98 kDa
NCBI Official Full Name
Stat2
NCBI Official Synonym Full Names
signal transducer and activator of transcription 2
NCBI Official Symbol
STAT2  [Similar Products]
NCBI Official Synonym Symbols
P113; IMD44; ISGF-3; STAT113
  [Similar Products]
NCBI Protein Information
signal transducer and activator of transcription 2
UniProt Protein Name
Signal transducer and activator of transcription 2
UniProt Synonym Protein Names
p113
UniProt Gene Name
STAT2  [Similar Products]
UniProt Entry Name
STAT2_HUMAN
NCBI Summary for Stat2
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
UniProt Comments for Stat2
STAT2: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Binds to the IFN-stimulated response element (ISRE) and to the Gas element. This multiprotein transcription factor is termed ISGF3. Two alternatively spliced isoforms have been described.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane

Molecular Function: DNA binding; identical protein binding; protein binding; signal transducer activity; transcription factor activity

Biological Process: cytokine and chemokine mediated signaling pathway; defense response to virus; JAK-STAT cascade; positive regulation of defense response to virus by host; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral reproduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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