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anti-gro2 antibody :: Rabbit Groucho 2 Polyclonal Antibody

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Catalog # MBS616829
Unit / Price
  0.05 mg  /  $350 +1 FREE 8GB USB
anti-gro2 antibody
Product Name

Groucho 2 (gro2), Polyclonal Antibody

Full Product Name

Groucho 2 (TLE2, ESG2, Transcription Factor)

Product Synonym Names
Anti -Groucho 2 (TLE2, ESG2, Transcription Factor)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 18; NC_007129.5 (20007518..20036903)
3D Structure
ModBase 3D Structure for O13166
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rodent
Specificity
Recognizes human Groucho 2 / TLE2 / ESG2 transcription factor.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS pH 7.2. No preservatives added.
Immunogen
Synthetic peptide corresponding to aa220-235, KEPSGPYESDEDKSDY from human Groucho 2, coupled with BSA.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-gro2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-gro2 antibody
Groucho2 (TLE2) (Transducin-Like Enhancer Protein 2, ESG2) is a member of the Groucho family of transcriptional corepressors. It inhibits the transcriptional activation mediated by b-catenin and TCF family members in Wnt signaling.
Applications Tested/Suitable for anti-gro2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-gro2 antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry: 1:200-1:1000
Western Blot: 1:200-1:1000
ELISA: 1:200-1:1000
NCBI/Uniprot data below describe general gene information for gro2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
82,460 Da[Similar Products]
NCBI Official Full Name
protein groucho-2
NCBI Official Synonym Full Names
groucho 2
NCBI Official Symbol
NCBI Official Synonym Symbols
zfgro2; GROUCHO2
  [Similar Products]
NCBI Protein Information
protein groucho-2; groucho-related Grg2
UniProt Protein Name
Protein groucho-2
UniProt Synonym Protein Names
Groucho-related Grg2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
grg2; groucho2  [Similar Products]
UniProt Entry Name
TLE2_DANRE
UniProt Comments for gro2
Function: Transcriptional corepressor that binds to a number of transcription factors

Subunit structure: Interacts with the WRPW motif of ripply1. Ref.2

Subcellular location: Nucleus

Probable.

Tissue specificity: Expressed ubiquitously during gastrulation. Expressed in the entire presomitic mesoderm, including the tailbud, throughout somitogenesis. Also expressed diffusely within whole somites in young stages. In older stages, expression is restricted to boundaries between somites. Also expressed in a dynamic manner within the neural plate. Ref.1

Developmental stage: Expressed both maternally and zygotically. Expression decreases from the midblastula stages onwards before increasing again at the start of gastrulation. Ref.1

Sequence similarities: Belongs to the WD repeat Groucho/TLE family.Contains 7 WD repeats.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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