• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ADAM8 antibody :: Rabbit anti-Mouse A Disintegrin And Metalloprotease 8 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS2027519 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $105 +1 FREE 8GB USB
  0.02 mg  /  $125 +1 FREE 8GB USB
  0.05 mg  /  $170 +1 FREE 8GB USB
  0.1 mg  /  $210 +1 FREE 8GB USB
  0.2 mg  /  $315 +1 FREE 8GB USB
  1 mg  /  $745 +1 FREE 8GB USB
Product Name

A Disintegrin And Metalloprotease 8 (ADAM8), Polyclonal Antibody

Also Known As

Polyclonal Antibody to A Disintegrin And Metalloprotease 8 (ADAM8)

Matching Pairs
Unconjugated Antibody: A Disintegrin And Metalloprotease 8 (MBS2027519)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
Matching Pairs
Unconjugated Antibody: A Disintegrin And Metalloprotease 8 (MBS2027519)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
824
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- EEGQHA MYQAKHLQQK AGTCGVKDTN LNDLGPRALE IYRAQPRNWL IPRETRYVEL YVVADSQEFQ KLGSREAVRQ RVLEVVNHVD KLYQELSFRV VLVGLEIWNK DKFYISRYAN VTLENFLSWR EQNLQGQHPH DNVQLITGVD FIGSTVGLAK VSALCSRHSG AVNQDHSKNS IGVASTMAHE LGHNLGMSHD EDIPGCYCPE PREGGGCIMT ESIGSKFPRI FSRCSKIDLE SFVTKPQTGC LTNVPDVNRF VGGPVCGNLF VEHGEQCDCG TPQDCQNPCC NATTCQLVKG AECASGTCCH
3D Structure
ModBase 3D Structure for Q05910
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Specificity
The antibody is a rabbit polyclonal antibody raised against ADAM8. It has beenselected for its ability to recognize ADAM8 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
200ug/ml (lot specific)
Fragment
ADAM8 (Glu145~Cys493)
Organism Species
Mus musculus (Mouse)
Conjugate
No Conjugate
Immunogen
Recombinant ADAM8 (Glu145~Cys493) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2045101
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-ADAM8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADAM8 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-ADAM8 antibody
Western blotting: 0.5-5ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-ADAM8 antibody
Western Blot: Sample: Lane1: Human Raji Cells; Lane2: Human Raw264.7 Cells; Lane3: Human 293T Cells; Lane4: Mouse Pancreas Tissue.
anti-ADAM8 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-ADAM8 antibody
Western Blot: Sample: Recombinant ADAM8, Mouse.
anti-ADAM8 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ADAM8 antibody
DAB staining on fromalin fixed paraffin-embedded Liver tissue)
anti-ADAM8 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ADAM8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
90,046 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 8 isoform 1
NCBI Official Synonym Full Names
a disintegrin and metallopeptidase domain 8
NCBI Official Symbol
Adam8  [Similar Products]
NCBI Official Synonym Symbols
MS2; CD156; ADAM 8; CD156a; E430039A18Rik
  [Similar Products]
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 8
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 8
UniProt Synonym Protein Names
Cell surface antigen MS2; Macrophage cysteine-rich glycoprotein; CD_antigen: CD156a
UniProt Gene Name
Adam8  [Similar Products]
UniProt Synonym Gene Names
Ms2; ADAM 8  [Similar Products]
NCBI Summary for ADAM8
This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]
UniProt Comments for ADAM8
ADAM8: Possible involvement in extravasation of leukocytes.

Protein type: EC 3.4.24.-; Membrane protein, integral; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 7|7 F4

Cellular Component: alpha9-beta1 integrin-ADAM8 complex; cell surface; cytoplasm; dense core granule membrane; integral component of membrane; integral component of plasma membrane; membrane; plasma membrane; podosome; specific granule

Molecular Function: calcium ion binding; cell adhesion molecule binding; hydrolase activity; integrin binding; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; protein binding; zinc ion binding

Biological Process: angiogenesis; blood vessel endothelial cell migration; cell morphogenesis; cell-matrix adhesion; cellular response to hypoxia; inflammatory response; leukocyte migration involved in inflammatory response; lymphocyte chemotaxis; negative regulation of neuron apoptosis; negative regulation of thymocyte aggregation; osteoclast fusion; positive regulation of acute inflammatory response; positive regulation of bone resorption; positive regulation of cell adhesion; positive regulation of cellular extravasation; positive regulation of eosinophil migration; positive regulation of fibronectin-dependent thymocyte migration; positive regulation of inflammatory response; positive regulation of innate immune response; positive regulation of MAP kinase activity; positive regulation of membrane protein ectodomain proteolysis; positive regulation of neutrophil extravasation; positive regulation of NF-kappaB transcription factor activity; positive regulation of protein kinase B signaling; positive regulation of T cell differentiation in thymus; positive regulation of T cell migration; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; proteolysis; regulation of cell-cell adhesion; regulation of osteoclast differentiation; tissue morphogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-ADAM8 antibody
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000