• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ADAMTS2 antibody :: anti-Mouse A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2) Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS2014630 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price DISCONTINUED
You will be redirected to our replacement product
anti-ADAMTS2 antibody
Product Name

A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2), Polyclonal Antibody

Also Known As

Biotin-Linked Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1211
Chromosome Location
Chromosome: 5; NC_000005.9 (178537852..178772431, complement). Location: 5qter
OMIM
225410
3D Structure
ModBase 3D Structure for O95450
Clonality
Polyclonal
Species Reactivity
Mouse
Concentration
200ug/ml (lot specific)
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-ADAMTS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-ADAMTS2 antibody
Applications Tested/Suitable for anti-ADAMTS2 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ADAMTS2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
134,755 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 1 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif, 2
NCBI Official Symbol
ADAMTS2  [Similar Products]
NCBI Official Synonym Symbols
NPI; PNPI; PCINP; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3
  [Similar Products]
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 2; procollagen I N-proteinase; procollagen N-endopeptidase; procollagen I/II amino propeptide-processing enzyme; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 2
UniProt Synonym Protein Names
Procollagen I N-proteinase; PC I-NP; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase
UniProt Gene Name
ADAMTS2  [Similar Products]
UniProt Synonym Gene Names
PCINP; PCPNI; ADAM-TS 2; ADAM-TS2; ADAMTS-2; PC I-NP; pNPI  [Similar Products]
UniProt Entry Name
ATS2_HUMAN
NCBI Summary for ADAMTS2
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
UniProt Comments for ADAMTS2
ADAMTS2: Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis. Defects in ADAMTS2 are the cause of Ehlers-Danlos syndrome type 7C (EDS7C). EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS7C is marked by extremely fragile tissues, hyperextensible skin and easy bruising. Facial skin contains numerous folds, as in the cutis laxa syndrome. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; EC 3.4.24.14; Protease; Motility/polarity/chemotaxis; Secreted, signal peptide; Extracellular matrix

Chromosomal Location of Human Ortholog: 5qter

Cellular Component: proteinaceous extracellular matrix; extracellular region

Molecular Function: metallopeptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: skin development; collagen catabolic process; extracellular matrix organization and biogenesis; collagen fibril organization; protein processing; spermatogenesis; proteolysis; lung development

Disease: Ehlers-danlos Syndrome, Type Vii, Autosomal Recessive
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000