• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ADAMTS2 antibody :: Rabbit anti-Mouse A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2) Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS2014980 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $110 +1 FREE 8GB USB
  0.02 mg  /  $130 +1 FREE 8GB USB
  0.05 mg  /  $185 +1 FREE 8GB USB
  0.1 mg  /  $230 +1 FREE 8GB USB
  0.2 mg  /  $345 +1 FREE 8GB USB
  1 mg  /  $825 +1 FREE 8GB USB
Product Name

A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2), Polyclonal Antibody

Also Known As

Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1211
Immunogen Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG S- VRHEWA LKKWSPCSKP CGGGSQFTKY GCRRRLDSKM VHRAFCSALA KPKAIRRACN PQECSQPVWV TGEWEPCTQS CGRTGMQVRS VRCIQPLHNN TTRSVHTKHC NDHRPESRRA CNRELCPGRW RAGSWSQCSV TCGNGTQERP
3D Structure
ModBase 3D Structure for Q8C9W3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Specificity
The antibody is a rabbit polyclonal antibody raised against ADAMTS2. It has been selected for its ability to recognize ADAMTS2 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
200ug/ml (lot specific)
Immunogen
Recombinant ADAMTS2 (Val855~Pro1030) expressed in E.coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2082103
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of anti-ADAMTS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADAMTS2 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-ADAMTS2 antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-ADAMTS2 antibody
Western Blot: Sample: Recombinant ADAMTS2, Mouse.
anti-ADAMTS2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ADAMTS2 antibody
DAB staining on IHC-P; Samples: Mouse Brain Tissue
anti-ADAMTS2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ADAMTS2 antibody
DAB staining on IHC-P; Samples: Mouse Uterus Tissue.
anti-ADAMTS2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ADAMTS2 antibody
DAB staining on IHC-P; Samples: Mouse Liver Tissue)
anti-ADAMTS2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ADAMTS2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
135,299 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 2 preproprotein
NCBI Official Synonym Full Names
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
NCBI Official Symbol
Adamts2  [Similar Products]
NCBI Official Synonym Symbols
pNPI; PCINP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAM-TS 2
  [Similar Products]
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 2
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 2
UniProt Synonym Protein Names
Procollagen I N-proteinase; PC I-NP; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase; pNPI
UniProt Gene Name
Adamts2  [Similar Products]
UniProt Synonym Gene Names
ADAM-TS 2; ADAM-TS2; ADAMTS-2; PC I-NP; pNPI  [Similar Products]
NCBI Summary for ADAMTS2
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin repeats) family of proteinases that is involved in the proteolytic processing of procollagens. The encoded protein precursor is proteolytically processed to generate a mature, zinc-dependent enzyme. Mice lacking the encoded protein develop abnormal lungs, fragile skin and male sterility. [provided by RefSeq, Aug 2015]
UniProt Comments for ADAMTS2
ADAMTS2: Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis. Defects in ADAMTS2 are the cause of Ehlers-Danlos syndrome type 7C (EDS7C). EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS7C is marked by extremely fragile tissues, hyperextensible skin and easy bruising. Facial skin contains numerous folds, as in the cutis laxa syndrome. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.14; Extracellular matrix; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11|11 B1.3

Cellular Component: extracellular region; extracellular space; proteinaceous extracellular matrix

Molecular Function: hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding

Biological Process: collagen catabolic process; collagen fibril organization; lung development; protein processing; proteolysis; skin development; spermatogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000