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anti-ABCC12 antibody :: Rabbit anti-Mouse ABCC12 Polyclonal Antibody

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Catalog # MBS9213897
Unit / Price
  0.08 mL  /  $150 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Product Name

ABCC12, Polyclonal Antibody

Also Known As

ABCC12 Antibody (Center)

Product Synonym Names
Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12; ABCC12; MRP9
Antibody/Peptide Pairs
ABCC12 peptide (MBS9219737) is used for blocking the activity of ABCC12 antibody (MBS9213897)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
723-752
Immunogen Sequence Length
930
OMIM
607041
3D Structure
ModBase 3D Structure for Q96J65
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Mouse
Specificity
This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the Central region of human ABCC12.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ABCC12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCC12 antibody
This gene is a member of the superfamily of ATP-binding
cassette (ABC) transporters and the encoded protein contains two
ATP-binding domains and 12 transmembrane regions. ABC proteins
transport various molecules across extra- and intracellular
membranes. ABC genes are divided into seven distinct subfamilies:
ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a
member of the MRP subfamily which is involved in multi-drug
resistance. This gene and another subfamily member are arranged
head-to-tail on chromosome 16q12.1. Increased expression of this
gene is associated with breast cancer.
Applications Tested/Suitable for anti-ABCC12 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ABCC12 antibody
WB~~1:1000

Western Blot (WB) of anti-ABCC12 antibody
ABCC12 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the ABCC12 antibody detected the ABCC12 protein (arrow).
anti-ABCC12 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABCC12 antibody
ABCC12 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCC12 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-ABCC12 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ABCC12. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
152297
NCBI Official Full Name
multidrug resistance-associated protein 9
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
NCBI Official Symbol
ABCC12  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
multidrug resistance-associated protein 9
UniProt Protein Name
Multidrug resistance-associated protein 9
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 12
Protein Family
UniProt Gene Name
ABCC12  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
MRP9_HUMAN
NCBI Summary for ABCC12
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCC12
ABCC12: Probable transporter. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, ABC family

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: mitochondrion; integral to membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP binding

Biological Process: metabolic process; transmembrane transport
Product References and Citations for anti-ABCC12 antibody
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Haimeur, A., et al. Curr. Drug Metab. 5(1):21-53(2004)
Bera, T.K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(10):6997-7002(2002)
Yabuuchi, H., et al. Biochem. Biophys. Res. Commun. 288(4):933-939(2001)
Tammur, J., et al. Gene 273(1):89-96(2001)

Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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