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anti-Aif1 antibody :: Rabbit anti-Mouse Allograft inflammatory factor 1 Polyclonal Antibody

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Catalog # MBS1494719
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Allograft inflammatory factor 1 (Aif1), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-mouse Allograft inflammatory factor 1 polyclonal Antibody

Product Synonym Names
onized calcium-binding adapter molecule 1; Iba1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O70200
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant mouse Allograft inflammatory factor 1 protein(2-147aa)
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-Aif1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Aif1 antibody
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Applications Tested/Suitable for anti-Aif1 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-Aif1 antibody
Western blot
All lanes: Allograft inflammatory factor 1 antibody at 2ug/ml+THP-1 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 17kDa
Observed band size: 17kDa

anti-Aif1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for Aif1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
16,911 Da
NCBI Official Full Name
allograft inflammatory factor 1
NCBI Official Synonym Full Names
allograft inflammatory factor 1
NCBI Official Symbol
NCBI Official Synonym Symbols
G1; Iba1; AIF-1; AI607846; D17H6S50E
  [Similar Products]
NCBI Protein Information
allograft inflammatory factor 1
UniProt Protein Name
Allograft inflammatory factor 1
UniProt Synonym Protein Names
Ionized calcium-binding adapter molecule 1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Iba1; AIF-1  [Similar Products]
UniProt Entry Name
AIF1_MOUSE
UniProt Comments for Aif1
AIF1: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Cellular Component: actin filament; cell projection; cytoplasm; cytoskeleton; cytosol; lamellipodium; membrane; nucleus; perikaryon; perinuclear region of cytoplasm; phagocytic cup; plasma membrane; ruffle

Molecular Function: actin binding; actin filament binding; calcium ion binding; metal ion binding; protein binding

Biological Process: actin filament bundle formation; actin filament polymerization; microglial cell activation; negative regulation of apoptosis; negative regulation of smooth muscle cell proliferation; phagocytosis, engulfment; positive regulation of cell migration; positive regulation of muscle hyperplasia; positive regulation of nitric oxide biosynthetic process; positive regulation of protein amino acid phosphorylation; positive regulation of smooth muscle cell proliferation; positive regulation of T cell proliferation; Rac protein signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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