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anti-CASR antibody :: Rabbit anti-Mouse Calcium Sensing Receptor (CASR) Polyclonal Antibody

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Catalog # MBS2065495 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
Scan QR to view Datasheet
  0.01 mg  /  $210 +1 FREE 8GB USB
  0.02 mg  /  $265 +1 FREE 8GB USB
  0.05 mg  /  $445 +1 FREE 8GB USB
  0.1 mg  /  $625 +1 FREE 8GB USB
  0.2 mg  /  $985 +1 FREE 8GB USB
  1 mg  /  $2,405 +3 FREE 8GB USB
anti-CASR antibody
Product Name

Calcium Sensing Receptor (CASR), Polyclonal Antibody

Full Product Name

APC/CY7-Linked Polyclonal Antibody to Calcium Sensing Receptor (CASR)

Product Synonym Names
CAR; FHH; FIH; GPRC2A; HHC; HHC1; NSHPT; PCAR1; Parathyroid cell calcium-sensing receptor 1; Hypocalciuric Hypercalcemia 1; Severe Neonatal Hyperparathyroidism
Matching Pairs
Unconjugated Antibody: Calcium Sensing (MBS2026057)
APC-CY7 Conjugated Antibody: Calcium Sensing Receptor (CASR) (MBS2065495)
Matching Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
X81086 Genomic DNA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Concentration
200ug/ml (lot specific)
Immunogen
CASR (Lys863~Ser1079)
Conjugation
APC-Cy7
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2026057
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CASR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CASR antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
NCBI/Uniprot data below describe general gene information for CASR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
121,772 Da
NCBI Official Full Name
calcium sensing receptor, partial
NCBI Official Synonym Full Names
calcium sensing receptor
NCBI Official Symbol
NCBI Official Synonym Symbols
CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; GPRC2A; HYPOC1
  [Similar Products]
NCBI Protein Information
extracellular calcium-sensing receptor
UniProt Protein Name
Extracellular calcium-sensing receptor
UniProt Synonym Protein Names
Parathyroid cell calcium-sensing receptor 1; PCaR1
UniProt Gene Name
UniProt Synonym Gene Names
GPRC2A; PCAR1; CaSR; PCaR1  [Similar Products]
NCBI Summary for CASR
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008]
UniProt Comments for CASR
CaR: a G-protein coupled receptor that activates a phosphatidylinositol-calcium second messenger system. Functions as a calcium sensor for parathyroid and kidney to determine the extracellular calcium concentration and thus helps to maintain a stable calcium concentration. Two alternatively-spliced isoforms have been described.

Protein type: GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3q13.33-q21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: phosphoinositide phospholipase C activity; protein binding

Biological Process: anatomical structure morphogenesis; cellular calcium ion homeostasis; chemosensory behavior; detection of calcium ion; ossification

Disease: Epilepsy, Idiopathic Generalized, Susceptibility To, 8; Hyperparathyroidism, Neonatal Severe; Hypocalcemia, Autosomal Dominant 1; Hypocalciuric Hypercalcemia, Familial, Type I
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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