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anti-Casein (kappa) antibody :: Rabbit anti-Mouse Casein (kappa) Polyclonal Antibody

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Catalog # MBS462214
Unit / Price
  0.1 mg  /  $265 +1 FREE 8GB USB
Testing Data
Product Name

Casein (kappa), Polyclonal Antibody

Also Known As

Rabbit anti Casein kappa Polyclonal antibody

Product Synonym Names
Rabbit anti-Csnk; Casein; Casein Kappa; Csnk; CSN10; CSN3.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Specificity
This antibody recognizes ~21 kDa of mouse Casein protein. The other species are not tested.
Purity/Purification
The Rabbit IgG is purified by Epitope Affinity Purification.
Form/Format
This affinity purified antibody is supplied in sterile phosphate-buffered saline (pH7.2) containing antibody stabilizer
Concentration
Size: 100 ug/200 ul (lot specific)
Antigen Preparation
A synthetic peptide corresponding to the N-terminus of mouse Casein protein.
Positive Control
Mouse mammary gland
Cellular Location
Cytoplasmic
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Other Notes
Small volumes of anti-Casein (kappa) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Casein (kappa) antibody
Casein is the predominant phosphoprotein which has no disulphide bridges but rich in proline. It is found in fresh milk, as a salt of calcium. Casein is not coagulated by heat. It is precipitated by acids and by rennet, a proteolytic enzyme typically obtained from the stomachs of calves. The enzyme trypsin can hydrolyze off a phosphate-containing peptone. This protein is synthesized by mammary epithelium only in the presence of lactogenic hormone combination of insulin, hydrocortisone, and prolactin. Enhancement of the rate of secretion of newly-synthesised caseins occurs when mammary explants are challenged in vitro with agents that activate protein kinase A (PKA). The PKA-sensitive step (s) in casein secretion is early in the exocytosis pathway but inhibition of PKA does not impair casein maturation. PKA is located on membranes of vesicles situated in the Golgi region. Casein positive cells are present in all breast carcinomas with a variable distribution and degree of staining. Casein serves as an in vitro marker of terminally differentiated breast luminal epithelial cells.
Applications Tested/Suitable for anti-Casein (kappa) antibody
ELISA, Western Blot
Application Notes for anti-Casein (kappa) antibody
Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml

Molecular Weight
~21 kDa
Product References and Citations for anti-Casein (kappa) antibody
P. Chandra Shekar et al. ?-Casein-deficient mice fail to lactate. PNAS 2006 May 23, 103 (21): 8000-8005

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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