CAG38558.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CCNB2
NCBI Official Synonym Full Names
cyclin B2
NCBI Official Synonym Symbols
NCBI Protein Information
G2/mitotic-specific cyclin-B2
UniProt Protein Name
G2/mitotic-specific cyclin-B2
UniProt Entry Name
CCNB2_HUMAN
NCBI Summary for CCNB2
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]
UniProt Comments for CCNB2
CCNB2: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Belongs to the cyclin family. Cyclin AB subfamily.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: microtubule cytoskeleton; nucleoplasm; centrosome; membrane; cytosol
Molecular Function: protein binding; protein kinase binding
Biological Process: mitosis; thymus development; regulation of cell cycle; in utero embryonic development; cell division; mitotic nuclear envelope disassembly; T cell homeostasis; mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; G2/M transition of mitotic cell cycle; growth
Research Articles on CCNB2
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Products associated with anti-CCNB2 antibody
Pathways associated with anti-CCNB2 antibody
Diseases associated with anti-CCNB2 antibody
Organs/Tissues associated with anti-CCNB2 antibody
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