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anti-CX43 antibody :: Rabbit anti-Mouse Connexin 43 Polyclonal Antibody

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Catalog # MBS2026016 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
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  0.01 mg  /  $105 +1 FREE 8GB USB
  0.02 mg  /  $125 +1 FREE 8GB USB
  0.05 mg  /  $170 +1 FREE 8GB USB
  0.1 mg  /  $210 +1 FREE 8GB USB
  0.2 mg  /  $315 +1 FREE 8GB USB
  1 mg  /  $745 +1 FREE 8GB USB
Product Name

Connexin 43 (CX43), Polyclonal Antibody

Popular Item
Full Product Name

Polyclonal Antibody to Connexin 43 (CX43)

Matching Pairs
Unconjugated Antibody: Connexin 43 (MBS2026016)
Immunogen: Connexin 43 (MBS2029380)
Matching Pairs
Unconjugated Antibody: Connexin 43 (MBS2026016)
APC-CY7 Conjugated Antibody: Connexin 43 (CX43) (MBS2040424)
Matching Pairs
Unconjugated Antibody: Connexin 43 (MBS2026016)
PE Conjugated Antibody: Connexin 43 (CX43) (MBS2040425)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
3D Structure
ModBase 3D Structure for P23242
Species Reactivity
The antibody is a rabbit polyclonal antibody raised against CX43. It has beenselected for its ability to recognize CX43 in immunohistochemical staining andwestern blotting.
Affinity Chromatography
200ug/ml (lot specific)
CX43 (Ser180~Ile382)
Organism Species
Mus musculus (Mouse)
No Conjugate
Recombinant CX43 (Ser180~Ile382) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2040426
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CX43 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CX43 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-CX43 antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-CX43 antibody
Western Blot: Sample: Mouse Brain Tissue.
anti-CX43 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-CX43 antibody
Western Blot: Sample: Recombinant CX43, Mouse.
anti-CX43 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CX43 antibody
DAB staining on IHC-P. Samples: Mouse Tissue)
anti-CX43 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CX43. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,004 Da
NCBI Official Full Name
gap junction alpha-1 protein
NCBI Official Synonym Full Names
gap junction protein, alpha 1
NCBI Official Symbol
NCBI Official Synonym Symbols
Cx43; Npm1; Cnx43; Gja-1; AU042049; AW546267; Cx43alpha1; connexin43
  [Similar Products]
NCBI Protein Information
gap junction alpha-1 protein
UniProt Protein Name
Gap junction alpha-1 protein
UniProt Synonym Protein Names
Connexin-43; Cx43; Gap junction 43 kDa heart protein
UniProt Gene Name
UniProt Synonym Gene Names
Cxn-43; Cx43  [Similar Products]
UniProt Comments for CX43
GJA1: an integral membrane protein of the connexin family, alpha-type (group II) subfamily. Hexamers of connexin-43 form connexons, which aggregate together to form gap junctions, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

Protein type: Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10 B4|10 28.64 cM

Cellular Component: apical plasma membrane; cell junction; connexin complex; contractile fiber; cytoplasm; cytosol; early endosome; endoplasmic reticulum; endosome; extracellular exosome; fascia adherens; focal adhesion; gap junction; Golgi apparatus; integral component of membrane; intercalated disc; intercellular junction; intermediate filament; late endosome; lateral plasma membrane; lysosome; membrane; membrane raft; mitochondrial outer membrane; mitochondrion; multivesicular body; plasma membrane; protein complex

Molecular Function: beta-tubulin binding; gap junction channel activity; gap junction channel activity involved in cardiac conduction electrical coupling; ion transmembrane transporter activity; PDZ domain binding; protein binding; protein domain specific binding; receptor binding; SH3 domain binding; signal transducer activity; transmembrane transporter activity

Biological Process: adult heart development; apoptosis; ATP transport; atrial ventricular junction remodeling; blood vessel morphogenesis; cell communication; cell communication by chemical coupling; cell communication by electrical coupling; cell-cell junction organization; cell-cell signaling; cellular response to pH; chronic inflammatory response; elevation of cytosolic calcium ion concentration; embryonic digit morphogenesis; embryonic heart tube development; epicardial cell to mesenchymal cell transition; epithelial cell maturation; establishment of epithelial cell polarity; heart development; heart looping; in utero embryonic development; lens development in camera-type eye; milk ejection reflex; negative regulation of cardiac muscle cell proliferation; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of DNA biosynthetic process; negative regulation of endothelial cell proliferation; negative regulation of gene expression; neuron migration; neuron projection morphogenesis; osteoblast differentiation; positive regulation of behavioral fear response; positive regulation of blood vessel diameter; positive regulation of cell communication by chemical coupling; positive regulation of gene expression; positive regulation of glomerular filtration; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of insulin secretion; positive regulation of osteoblast differentiation; positive regulation of protein catabolic process; positive regulation of striated muscle tissue development; positive regulation of vasoconstriction; protein oligomerization; regulation of bicellular tight junction assembly; regulation of bone mineralization; regulation of bone remodeling; regulation of calcium ion transport; regulation of heart contraction; regulation of transmembrane transporter activity; response to pH; signal transduction; skeletal muscle tissue regeneration; transmembrane transport; vascular transport
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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