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anti-FAPa antibody :: Rabbit anti-Mouse Fibroblast Activation Protein Alpha (FAPa) Polyclonal Antibody

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Catalog # MBS2065904 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $165 +1 FREE 8GB USB
  0.02 mg  /  $200 +1 FREE 8GB USB
  0.05 mg  /  $305 +1 FREE 8GB USB
  0.1 mg  /  $430 +1 FREE 8GB USB
  0.2 mg  /  $665 +1 FREE 8GB USB
  1 mg  /  $1,610 +2 FREE 8GB USB
anti-FAPa antibody
Product Name

Fibroblast Activation Protein Alpha (FAPa), Polyclonal Antibody

Popular Item
Full Product Name

Cy3-Linked Polyclonal Antibody to Fibroblast Activation Protein Alpha (FAPa)

Product Synonym Names
APCE; SIMP; DPPIV; Seprase; 170 kDa melanoma membrane-bound gelatinase; Post-proline cleaving enzyme; Serine integral membrane protease; Surface-expressed protease
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2065904 Technical Datasheet
OMIM
U09278 mRNA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Purity/Purification
Antigen-specific Affinity Chromatography
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
0.5 mg/ml (lot specific)
Organism Species
Mus musculus (Mouse)
Source
Antibody labeling
Label
Biotin
Traits
Cy3
Immunogen
Recombinant FAPa (Gly542~Asp761) expressed in E.coli.
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2026729
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20oC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-FAPa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-FAPa antibody
WB; IHC; ICC; IP.
Application Notes for anti-FAPa antibody
Western blotting: 0.5-2 ug/mL;1:250-1000
Immunohistochemistry: 5-20 ug/mL;1:25-100
Immunocytochemistry: 5-20 ug/mL;1:25-100

Optimal working dilutions must be determined by end user.
NCBI/Uniprot data below describe general gene information for FAPa. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
fibroblast activation protein, alpha, isoform CRA_b
NCBI Official Synonym Full Names
fibroblast activation protein alpha
NCBI Official Symbol
NCBI Official Synonym Symbols
FAPA; SIMP; DPPIV; FAPalpha
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NCBI Protein Information
prolyl endopeptidase FAP
UniProt Protein Name
Prolyl endopeptidase FAP
UniProt Synonym Protein Names
170 kDa melanoma membrane-bound gelatinase
UniProt Gene Name
UniProt Synonym Gene Names
NCBI Summary for FAPa
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
UniProt Comments for FAPa
FAP: In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers. Belongs to the peptidase S9B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.14.5; EC 3.4.21.26; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 2q24.2

Cellular Component: cell surface; extracellular space; focal adhesion; lamellipodium; plasma membrane

Molecular Function: dipeptidyl-peptidase activity; endopeptidase activity; integrin binding; metalloendopeptidase activity; peptidase activity; protease binding; protein binding; protein homodimerization activity; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: endothelial cell migration; proteolysis; proteolysis involved in cellular protein catabolic process; regulation of fibrinolysis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-FAPa antibody
 Reference Product  PubMed Publications
 DPP4 antibody  >13 publications with FAPa and DPP4
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