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anti-PTPRS antibody :: Rabbit anti-Mouse Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Polyclonal Antibody

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Catalog # MBS2014690 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.1 mg  /  $255 +1 FREE 8GB USB
anti-PTPRS antibody
Product Name

Protein Tyrosine Phosphatase Receptor Type S (PTPRS), Polyclonal Antibody

Popular Item
Also Known As

FITC-linked Antibody to Protein Tyrosine Phosphatase Receptor Type S (PTPRS)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 19; NC_000019.9 (5205514..5340814, complement). Location: 19p13.3
OMIM
601576
3D Structure
ModBase 3D Structure for Q13332
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Purity/Purification
Antigen-specific Affinity Chromatography
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
Concentration
200ug/ml (lot specific)
Source
Antibody labeling
Label
FITC
Traits
Liquid
Immunogen
Recombinant PTPRS (Arg889~His1102) expressed in E.coli
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
Other Notes
Small volumes of anti-PTPRS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-PTPRS antibody
Applications Tested/Suitable for anti-PTPRS antibody
WB; IHC; ICC; IF
Application Notes for anti-PTPRS antibody
Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL

Optimal working dilutions must be determined by end user
NCBI/Uniprot data below describe general gene information for PTPRS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
protein tyrosine phosphatase, receptor type, S, isoform CRA_h
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, S
NCBI Official Symbol
PTPRS  [Similar Products]
NCBI Official Synonym Symbols
PTPSIGMA
  [Similar Products]
NCBI Protein Information
receptor-type tyrosine-protein phosphatase S; R-PTP-S; R-PTP-sigma; protein tyrosine phosphatase PTPsigma; receptor-type tyrosine-protein phosphatase sigma; protein tyrosine phosphatase, receptor type, sigma
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase S
UniProt Synonym Protein Names
Receptor-type tyrosine-protein phosphatase sigma
UniProt Gene Name
PTPRS  [Similar Products]
UniProt Synonym Gene Names
R-PTP-S; R-PTP-sigma  [Similar Products]
UniProt Entry Name
PTPRS_HUMAN
NCBI Summary for PTPRS
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for PTPRS
PTPRS: Interacts with LAR-interacting protein LIP.1. Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.1.3.48; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane

Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity

Biological Process: corpus callosum development; extracellular matrix organization and biogenesis; spinal cord development; hippocampus development; cerebellum development; cerebral cortex development; cell adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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