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anti-Acacb antibody :: Goat Acacb Polyclonal Antibody

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Catalog # MBS423411
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
anti-Acacb antibody
Product Name

Acacb, Polyclonal Antibody

Also Known As

Goat anti-Acacb (mouse) Antibody

Product Synonym Names
Acacb; acetyl-CoA carboxylase beta; Acc2; Accb; AI597064; AW743042; Acacb antibody; acetyl-CoA carboxylase beta antibody; Acc2 antibody; Accb antibody; AI597064 antibody; AW743042 antibody; antibody; antibody; Acacb (mouse)
Antibody/Peptide Pairs
Acacb peptide (MBS428524) is used for blocking the activity of Acacb antibody (MBS423411)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
2448
Immunogen Sequence
TLNVQESGRV KYIKR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Mouse, Rat, Pig
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-TLNVQESGRVKYIKR, from the internal region of the protein sequence according to NP_598665.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-Acacb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-Acacb antibody
Peptide ELISA (EIA)
Application Notes for anti-Acacb antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 277kDa according to NP_001084.3. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
NCBI/Uniprot data below describe general gene information for Acacb. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
275,750 Da
NCBI Official Full Name
acetyl-CoA carboxylase 2
NCBI Official Synonym Full Names
acetyl-Coenzyme A carboxylase beta
NCBI Official Symbol
Acacb  [Similar Products]
NCBI Official Synonym Symbols
Acc2; Accb; AI597064; AW743042
  [Similar Products]
NCBI Protein Information
acetyl-CoA carboxylase 2
UniProt Protein Name
Acetyl-CoA carboxylase 2
UniProt Synonym Protein Names
ACC-beta
UniProt Gene Name
Acacb  [Similar Products]
UniProt Entry Name
ACACB_MOUSE
UniProt Comments for Acacb
ACC2: a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Activity is increased by oligomerization. Activated by citrate. Citrate and MID1IP1 promote oligomerization. Inhibited by malonyl-CoA. ACC1 is the predominant form expressed in liver, adipocyte and mammary gland. Phosphorylation by AMPK or PKA inhibits the enzymatic activity of ACC. ACC2 is the major isoform in skeletal muscle and heart. Phosphorylation regulates its activity. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Lipid Metabolism - fatty acid biosynthesis; Carbohydrate Metabolism - propanoate; EC 6.4.1.2; EC 6.3.4.14; Carbohydrate Metabolism - pyruvate; Ligase

Cellular Component: membrane; mitochondrion; nucleus

Molecular Function: acetyl-CoA carboxylase activity; ATP binding; biotin binding; biotin carboxylase activity; catalytic activity; ligase activity; metal ion binding; nucleotide binding

Biological Process: acetyl-CoA metabolic process; fatty acid biosynthetic process; fatty acid metabolic process; lipid metabolic process; metabolic process; negative regulation of catalytic activity; negative regulation of fatty acid beta-oxidation; negative regulation of fatty acid oxidation; negative regulation of lipid catabolic process; protein homotetramerization; response to nutrient levels; response to organic cyclic substance
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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