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anti-SELL antibody :: Rabbit anti-Mouse, Rat CD62L Polyclonal Antibody

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Catalog # MBS175447
Unit / Price
  0.1 mg  /  $280 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CD62L (SELL), Polyclonal Antibody

Popular Item
Full Product Name

Anti-CD62L antibody

Product Synonym Names
L-selectin; selectin L; A.11 antibody; AI528707 antibody; CD62 antigen ligand antibody; CD62 antigen-like family member L antibody; CD62L antibody; gp90 MEL antibody; gp90-MEL antibody; hLHRc antibody; IgA nephropathy, susceptibility to, included antibody; L Selectin antibody; L-selectin antibody; LAM-1 antibody; LAM1 antibody; LECAM1 antibody; LEU8 antibody; Leukocyte adhesion molecule 1 antibody; Leukocyte surface antigen Leu-8 antibody; Leukocyte surface antigen Leu8 antibody; Leukocyte-endothelial cell adhesion molecule 1 antibody; LNHR antibody; LSEL antibody; Ly-22 antibody; Ly-m22 antibody; Lyam-1 antibody; LYAM1 antibody; LYAM1_HUMAN antibody; Lymph node homing receptor antibody; Lymphocyte adhesion molecule 1 antibody; Lymphocyte antigen 22 antibody; Lymphocyte surface MEL-14 antigen antibody; MEL-14 antibody; Pln homing receptor antibody; PLNHR antibody; Selectin L antibody; Selectin, lymphocyte antibody; SELL antibody; TQ1 antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P18337
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse CD62L (125-141aa KEDCVEIYIKRERDSGK), identical to the related rat sequence.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SELL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SELL antibody
Description: Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB in Mouse, Rat.
Background: L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL(L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.
Applications Tested/Suitable for anti-SELL antibody
Western Blot (WB)

Western Blot (WB) of anti-SELL antibody
Anti- L-selectin antibody, MBS175447, Western blotting
All lanes: Anti L-selectin (MBS175447) at 0.5ug/ml
Lane 1: Rat Spleen Tissue Lysate at 50ug
Lane 2: Mouse Spleen Tissue Lysate at 50ug
Predicted bind size: 42KD
Observed bind size: 70KD
anti-SELL antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SELL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
42,288 Da
NCBI Official Full Name
L-selectin
NCBI Official Synonym Full Names
selectin, lymphocyte
NCBI Official Symbol
NCBI Official Synonym Symbols
Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin
  [Similar Products]
NCBI Protein Information
L-selectin; LAM-1; LECAM1; lymphocyte antigen 22; lymph node homing receptor; leukocyte adhesion molecule 1; CD62 antigen-like family member L; lymphocyte surface MEL-14 antigen; leukocyte-endothelial cell adhesion molecule 1
UniProt Protein Name
L-selectin
UniProt Synonym Protein Names
CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; Ly-22; Lymphocyte surface MEL-14 antigen; CD_antigen: CD62L
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Lnhr; Ly-22; Ly22; LAM-1; LECAM1; Ly-22  [Similar Products]
UniProt Entry Name
LYAM1_MOUSE
UniProt Comments for SELL
SELL: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Belongs to the selectin/LECAM family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; protease binding; cell adhesion molecule binding; carbohydrate binding; glycolipid binding

Biological Process: regulation of apoptosis; cell adhesion; response to ATP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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