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anti-Slc19a1 antibody :: Goat SLC19A1/RFC1 Polyclonal Antibody

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Catalog # MBS422803
Unit / Price
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  0.1 mg  /  $225 +1 FREE 8GB USB
anti-Slc19a1 antibody
Product Name

SLC19A1/RFC1, Polyclonal Antibody

Popular Item
Full Product Name

Goat anti-SLC19A1/RFC1 (mouse) Antibody

Product Synonym Names
Slc19a1; solute carrier family 19 (folate transporter), member 1; AI323572; RFC; RFC-1; RFC1; IFC-1; OTTMUSP00000045639; OTTMUSP00000045641; folate transporter 1; intestinal folate carrier 1; intestinal folate carrier protein; reduced folate carrier 1; so; Slc19a1 antibody; solute carrier family 19 (folate transporter); member 1 antibody; AI323572 antibody; RFC antibody; RFC-1 antibody; RFC1 antibody; IFC-1 antibody; OTTMUSP00000045639 antibody; OTTMUSP00000045641 antibody; folate transporter 1 antibody; intestinal folate carrier 1 antibody; intestinal folate carrier protein antibody; reduced folate carrier 1 antibody; solute carrier family 19 member 1 antibody; SLC19A1 / RFC1 (mouse)
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
KQAYEEPRQD HELK
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Mouse, Rat
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence KQAYEEPRQDHELK-C, from the N Terminus of the protein sequence according to NP_112473.1.
Epitope
N Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-Slc19a1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-Slc19a1 antibody
Peptide ELISA (EIA)
Application Notes for anti-Slc19a1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Preliminary experiments gave bands at approx 65kDa and 26kDa in Mouse Skin lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 58.2kDa according to NP_112473.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
NCBI/Uniprot data below describe general gene information for Slc19a1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,371 Da
NCBI Official Full Name
folate transporter 1
NCBI Official Synonym Full Names
solute carrier family 19 (folate transporter), member 1
NCBI Official Symbol
Slc19a1  [Similar Products]
NCBI Official Synonym Symbols
RFC; RFC1; RFC-1; AI323572
  [Similar Products]
NCBI Protein Information
folate transporter 1
UniProt Protein Name
Folate transporter 1
UniProt Synonym Protein Names
Intestinal folate carrier 1; IFC-1; Reduced folate carrier 1; RFC-1; RFC1; Solute carrier family 19 member 1
UniProt Gene Name
Slc19a1  [Similar Products]
UniProt Synonym Gene Names
IFC-1; RFC-1; RFC1  [Similar Products]
UniProt Entry Name
S19A1_MOUSE
UniProt Comments for Slc19a1
SLC19A1: a transporter protein. Transports reduced folate, antitumor agents and folate antagonists such as methotrexate. Apparently involved in methotrexate resistance in various cancers and neural tube defects.

Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter

Cellular Component: apical plasma membrane; basolateral plasma membrane; brush border membrane; integral to membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: folic acid binding; folic acid transporter activity; methotrexate transporter activity; reduced folate carrier activity

Biological Process: folic acid transport; methotrexate transport; transmembrane transport; transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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