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anti-TLR13 antibody :: Rabbit anti-Mouse, Rat TLR13 Polyclonal Antibody

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Catalog # MBS5400086
Unit / Price
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  0.1 mg  /  $390 +1 FREE 8GB USB
Product Name

TLR13, Polyclonal Antibody

Popular Item
Full Product Name

TLR13 Antibody

Product Synonym Names
Toll like receptor 13 antibody
Matching Pairs
Antibody: TLR13 (MBS5400086)
Positive Control: TLR13 (MBS543321)
Antibody/Peptide Pairs
TLR13 peptide (MBS544577) is used for blocking the activity of TLR13 antibody (MBS5400086)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6R5N8
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.68 ug/ul in antibody stabilization buffer (lot specific)
Immunogen
Synthetic peptide taken within amino acid region 400-480 of mouse TLR13 protein.
Molecular Function
protein homodimerization activity, rRNA binding
Subcellular Location
endosome membrane, Single-pass type I membrane protein
Preparation and Storage
-20 degree C for long term storage
Other Notes
Small volumes of anti-TLR13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TLR13 antibody
Affinity Purified Toll-like receptor 13 Antibody
Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Applications Tested/Suitable for anti-TLR13 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-TLR13 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500

Immunohistochemistry (IHC) of anti-TLR13 antibody
anti-TLR13 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-TLR13 antibody
anti-TLR13 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for TLR13. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
114,443 Da
NCBI Official Full Name
Toll-like receptor 13
NCBI Official Synonym Full Names
toll-like receptor 13
NCBI Official Symbol
Tlr13  [Similar Products]
NCBI Official Synonym Symbols
Gm713; AI666735
  [Similar Products]
NCBI Protein Information
toll-like receptor 13
UniProt Protein Name
Toll-like receptor 13
Protein Family
UniProt Gene Name
Tlr13  [Similar Products]
UniProt Entry Name
TLR13_MOUSE
UniProt Comments for TLR13
TLR13: Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences. Belongs to the Toll-like receptor family.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: cytoplasm; endosome; integral to membrane; membrane

Molecular Function: double-stranded RNA binding; protein binding; protein homodimerization activity; RNA binding; rRNA binding

Biological Process: immune system process; inflammatory response; innate immune response; MyD88-dependent toll-like receptor signaling pathway; regulation of MAPKKK cascade; response to virus; signal transduction; toll-like receptor 13 signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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