NP_038866.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
106,681 Da
NCBI Official Full Name
short transient receptor potential channel 6 isoform 1
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily C, member 6
NCBI Official Synonym Symbols
TRP-6; Trrp6; mtrp6; AV025995; LLHWJM002; LLHWJM003; LLHWJM004 [Similar Products]
NCBI Protein Information
short transient receptor potential channel 6
UniProt Protein Name
Short transient receptor potential channel 6
UniProt Synonym Protein Names
Calcium entry channel; Transient receptor protein 6; TRP-6
UniProt Synonym Gene Names
UniProt Entry Name
TRPC6_MOUSE
UniProt Comments for Trpc6
TRPC6: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. Interacts with MX1 and RNF24. Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, cation
Cellular Component: cytoplasm; cytosol; integral to membrane; integral to plasma membrane; membrane; plasma membrane
Molecular Function: actin binding; actinin binding; ATPase binding; calcium channel activity; cation channel activity; clathrin binding; ion channel activity; protein binding; store-operated calcium channel activity
Biological Process: calcium ion transport; elevation of cytosolic calcium ion concentration; ion transport; manganese ion transport; negative regulation of dendrite morphogenesis; positive regulation of calcium ion transport; positive regulation of ion transmembrane transporter activity; positive regulation of neuron differentiation; single fertilization; transmembrane transport; transport
Research Articles on Trpc6
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Products associated with anti-Trpc6 antibody
Pathways associated with anti-Trpc6 antibody
Diseases associated with anti-Trpc6 antibody
Organs/Tissues associated with anti-Trpc6 antibody
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