NP_001193769.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,541 Da
NCBI Official Full Name
trans-Golgi network integral membrane protein 2 isoform 2
NCBI Official Synonym Full Names
trans-golgi network protein 2
NCBI Official Synonym Symbols
TGN38; TGN46; TGN48; TGN51; TTGN2 [Similar Products]
NCBI Protein Information
trans-Golgi network integral membrane protein 2; TGN38 homolog; trans-Golgi network protein (46, 48, 51kD isoforms); trans-Golgi network protein TGN51
UniProt Protein Name
Trans-Golgi network integral membrane protein 2
UniProt Synonym Protein Names
TGN38 homolog; TGN46; TGN48; Trans-Golgi network protein TGN51
UniProt Synonym Gene Names
UniProt Entry Name
TGON2_HUMAN
NCBI Summary for TGN46
This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for TGN46
TGOLN2: May be involved in regulating membrane traffic to and from trans-Golgi network. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: nucleoplasm; Golgi apparatus; transport vesicle; plasma membrane; integral to membrane; trans-Golgi network
Molecular Function: protein binding
Research Articles on TGN46
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Pathways associated with anti-TGN46 antibody
Diseases associated with anti-TGN46 antibody
Organs/Tissues associated with anti-TGN46 antibody
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