G3V9N4
[Other Products]
Molecular Weight
84,556 Da
UniProt Protein Name
A disintegrin and metallopeptidase domain 6
UniProt Synonym Protein Names
A disintegrin and metallopeptidase domain 6
NCBI Summary for ADAM6
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]
UniProt Comments for ADAM6
ADAMTS6: a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]
Protein type: Protease; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted; EC 3.4.24.-
Chromosomal Location of Human Ortholog: 5q12
Cellular Component: proteinaceous extracellular matrix
Molecular Function: metallopeptidase activity; zinc ion binding; metalloendopeptidase activity
Biological Process: proteolysis
Research Articles on ADAM6
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Organs/Tissues associated with anti-ADAM6 antibody
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