anti-ADAM6 antibody :: Rabbit anti-Rat A Disintegrin And Metalloprotease 6 (ADAM6) Polyclonal Antibody

Catalog #	MBS2006770 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price	0.01 mg / $120 +1 FREE 8GB USB 0.02 mg / $140 +1 FREE 8GB USB 0.05 mg / $200 +1 FREE 8GB USB 0.1 mg / $260 +1 FREE 8GB USB 0.2 mg / $400 +1 FREE 8GB USB 1 mg / $950 +1 FREE 8GB USB

Product Name

A Disintegrin And Metalloprotease 6 (ADAM6), Polyclonal Antibody

Polyclonal Antibody to A Disintegrin And Metalloprotease 6 (ADAM6)

Product Gene Name

anti-ADAM6 antibody

[Similar Products]

Matching Pairs

Unconjugated Antibody: A Disintegrin And Metalloprotease 6 (ADAM6) (MBS2006770)
Immunogen: A Disintegrin And Metalloprotease 6 (ADAM6) (MBS2011974)

Matching Pairs

Unconjugated Antibody: A Disintegrin And Metalloprotease 6 (ADAM6) (MBS2006770)
APC-CY7 Conjugated Antibody: A Disintegrin And Metalloprotease 6 (ADAM6) (MBS2085501)

Matching Pairs

Unconjugated Antibody: A Disintegrin And Metalloprotease 6 (ADAM6) (MBS2006770)
PE Conjugated Antibody: A Disintegrin And Metalloprotease 6 (ADAM6) (MBS2085502)

Research Use Only

For Research Use Only. Not for use in diagnostic procedures.

Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF-FC GNFKIDIGEQ CDCGSHKACY ADPCCGSNCK LTAGSICDKE LCCANCTYSP SGTLCRPIQN ICDLPEYCSG NNIFCPADTY LQDGTPCSEE GYCYKGNCTD RSVQCKEIFG VNAKGANIKC YDINKQRFRF GHCTRAQESL MFNACSDHDK LCGRLQCTNV TNLPFLQEHV SFHQSVISGF TCFGLDEHRG TETTDAGLVK HGTPCSQTNF CDRGACNGSL SRLDYDCTPE KCNFRGVCNN HRHC

3D Structure

ModBase 3D Structure for G3V9N4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Rat

Specificity

The antibody is a rabbit polyclonal antibody raised against ADAM6. It has been selected for its ability to recognize ADAM6 in immunohistochemical staining andwestern blotting.

Purity/Purification

Affinity Chromatography

Form/Format

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

Concentration

200ug/ml (lot specific)

Immunogen

Recombinant ADAM6 (Phe419~Cys664) expressed in E.coli.

Conjugated Antibody

The APC conjugated antibody version of this item is also available as catalog #MBS2085503

Preparation and Storage

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

ISO Certification

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.

Other Notes

Small volumes of anti-ADAM6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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Applications Tested/Suitable for anti-ADAM6 antibody

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

Application Notes for anti-ADAM6 antibody

Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-ADAM6 antibody

Western Blot: Sample: Recombinant protein.

anti-ADAM6 antibody Western Blot (WB) (WB) image

Immunohistochemistry (IHC) of anti-ADAM6 antibody

DABstainingonIHC-P.Samples:RatTissue)

anti-ADAM6 antibody Immunohistochemistry (IHC) (IHC) image

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NCBI/Uniprot data below describe general gene information for ADAM6. It may not necessarily be applicable to this product.

UniProt Primary Accession #

G3V9N4 [Other Products]

Molecular Weight

84,556 Da

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UniProt Protein Name

A disintegrin and metallopeptidase domain 6

UniProt Synonym Protein Names

A disintegrin and metallopeptidase domain 6

UniProt Gene Name

Adam6 [Similar Products]

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NCBI Summary for ADAM6

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]

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UniProt Comments for ADAM6

ADAMTS6: a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]

Protein type: Protease; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 5q12

Cellular Component: proteinaceous extracellular matrix

Molecular Function: metallopeptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis

Research Articles on ADAM6

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

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Organs/Tissues associated with anti-ADAM6 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>7 publications with ADAM6 and Testis