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anti-A2m antibody :: Goat anti-Rat Alpha 2-Macroglobulin Polyclonal Antibody

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Catalog # MBS560662
Unit / Price
  0.1 mg  /  $250 +1 FREE 8GB USB
anti-A2m antibody
Product Name

Alpha 2-Macroglobulin (A2m), Polyclonal Antibody

Popular Item
Also Known As

Affinity Purified Goat anti-Rat Alpha 2-Macroglobulin

Product Synonym Names
Affinity PurifiedGoat anti-Rat Alpha 2-Macroglobulin; anti-Rat Alpha 2-Macroglobulin
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 6; NC_000072.5 (128433585..128476738, complement). Location: 6 F1-G3; 6 62.0 cM
3D Structure
ModBase 3D Structure for Q61838
Clonality
Polyclonal
Host
Goat
Species Reactivity
Rat
Purity/Purification
Unconjugated A.P.
Form/Format
Liquid
Preservative
0.1% sodium azide
Procedure
Goats were immunized with rat Alpha 2-Macroglobulin isolated from acute phase rat serum. The resulting antiserum was solid phase absorbed with rat serum lacking alpha 2- macroglobulin until it gave a single band with serum containing the acute phase protein. The specific antibodies were then immunoaffinity purified off an antigen containing immunoabsorbant.
Preparation and Storage
Store at 4 degree C.
Shelf Life: 12 months from shipment date
Other Notes
Small volumes of anti-A2m antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-A2m antibody
Goats were immunized with rat Alpha 2-Macroglobulin (A2M). The resulting antiserum was passed over an antigen containing immunoabsorbant from which the anti-rat A2M was immunoaffinity purified.
Product Categories/Family for anti-A2m antibody
Application Notes for anti-A2m antibody
The Goat anti-Rat A2M gives a single band against acute phase rat serum by IEP and gel diffusion analysis. This product is suitable for ELISA and blotting applications.
NCBI/Uniprot data below describe general gene information for A2m. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
165,853 Da[Similar Products]
NCBI Official Full Name
alpha-2-macroglobulin
NCBI Official Synonym Full Names
pregnancy zone protein
NCBI Official Synonym Symbols
A1m; A2m; MAM; AI893533
  [Similar Products]
NCBI Protein Information
alpha-2-macroglobulin; alpha-2-M; OTTMUSP00000025075; alpha 1 macroglobulin
UniProt Protein Name
Alpha-2-macroglobulin
UniProt Synonym Protein Names
Pregnancy zone protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
A2M_MOUSE
UniProt Comments for A2m
PZP: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; protease inhibitor activity; endopeptidase inhibitor activity; protein complex binding

Biological Process: negative regulation of peptidase activity; embryo implantation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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