NP_619635.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW: 113kDa Molecular Weight: 1043
NCBI Official Full Name
glutamate receptor ionotropic, NMDA 3B
NCBI Official Synonym Full Names
glutamate ionotropic receptor NMDA type subunit 3B
NCBI Official Synonym Symbols
NCBI Protein Information
glutamate receptor ionotropic, NMDA 3B
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 3B
UniProt Synonym Protein Names
N-methyl-D-aspartate receptor subtype 3B; NMDAR3B; NR3B
UniProt Synonym Gene Names
UniProt Entry Name
NMD3B_HUMAN
NCBI Summary for GRIN3B
The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia. [provided by RefSeq, Nov 2015]
UniProt Comments for GRIN3B
NMDAR3B: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cell junction; cell soma; N-methyl-D-aspartate selective glutamate receptor complex; postsynaptic membrane
Molecular Function: calcium channel activity; cation channel activity; extracellular-glutamate-gated ion channel activity; glycine binding; N-methyl-D-aspartate selective glutamate receptor activity; neurotransmitter binding; neurotransmitter receptor activity
Biological Process: ionotropic glutamate receptor signaling pathway; protein insertion into membrane; regulation of calcium ion transport; synaptic transmission
Research Articles on GRIN3B
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Pathways associated with anti-GRIN3B antibody
Diseases associated with anti-GRIN3B antibody
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