NP_001099960.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
myosin-binding protein C, cardiac-type
NCBI Official Synonym Full Names
myosin binding protein C, cardiac
NCBI Protein Information
myosin-binding protein C, cardiac-type
UniProt Protein Name
Myosin-binding protein C, cardiac-type
UniProt Synonym Protein Names
C-protein, cardiac muscle isoform
UniProt Synonym Gene Names
UniProt Entry Name
MYPC_RAT
UniProt Comments for Mybpc3
MYBPC3: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family.
Protein type: Myosin-binding
Cellular Component: A band; myofibril; sarcomere; striated muscle thick filament
Molecular Function: actin binding; identical protein binding; metal ion binding; myosin binding; myosin heavy chain binding; structural constituent of muscle
Biological Process: cardiac muscle contraction; cell adhesion; heart morphogenesis; muscle contraction; myosin filament assembly; regulation of heart contraction; regulation of heart rate; regulation of striated muscle contraction; sarcomere organization; ventricular cardiac muscle morphogenesis
Research Articles on Mybpc3
Precautions
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Products associated with anti-Mybpc3 antibody
Pathways associated with anti-Mybpc3 antibody
Diseases associated with anti-Mybpc3 antibody
Disease Name |
Pubmed Publications |
Cardiomyopathy, Hypertrophic Antibodies |
>243 publications with Mybpc3 and Cardiomyopathy, Hypertrophic |
Heart Diseases Antibodies |
>240 publications with Mybpc3 and Heart Diseases |
Cardiomyopathies Antibodies |
>225 publications with Mybpc3 and Cardiomyopathies |
Hypertrophy Antibodies |
>93 publications with Mybpc3 and Hypertrophy |
Cardiomyopathy, Hypertrophic, Familial Antibodies |
>90 publications with Mybpc3 and Cardiomyopathy, Hypertrophic, Familial |
Death, Sudden, Cardiac Antibodies |
>58 publications with Mybpc3 and Death, Sudden, Cardiac |
Cardiomegaly Antibodies |
>42 publications with Mybpc3 and Cardiomegaly |
Cardiomyopathy, Dilated Antibodies |
>37 publications with Mybpc3 and Cardiomyopathy, Dilated |
Cardiomyopathy, Familial Hypertrophic, 4 Antibodies |
>27 publications with Mybpc3 and Cardiomyopathy, Familial Hypertrophic, 4 |
Fibrosis Antibodies |
>13 publications with Mybpc3 and Fibrosis |
Organs/Tissues associated with anti-Mybpc3 antibody
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