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anti-nr2B antibody :: Rabbit anti-Rat NMDA Receptor NR2B Polyclonal Antibody

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Catalog # MBS624754
Unit / Price
  0.1 mL  /  $755 +1 FREE 8GB USB
anti-nr2B antibody
Product Name

NMDA Receptor NR2B, Polyclonal Antibody

Also Known As

NMDA Receptor NR2B, phosphorylated (Tyr1472) (NMDA R2b, NMDAR2B, N-methyl-D-aspartate, GRIN2B, Glutamate [NMDA] Receptor Subunit epsilon-2, NR2B, N-methyl-D-aspartate Receptor Subunit 2B)

Product Synonym Names
Anti -NMDA Receptor NR2B, phosphorylated (Tyr1472) (NMDA R2b, NMDAR2B, N-methyl-D-aspartate, GRIN2B, Glutamate [NMDA] Receptor Subunit epsilon-2, NR2B, N-methyl-D-aspartate Receptor Subunit 2B)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for B5QTB1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Specificity
Recognizes the 180kD NR2B subunit of rat NMDA receptor when phosphorylated at Tyr1472. Species sequence homology: zebrafish, bovine, human, monkey, mouse, canine, chicken.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in 10mM Hepes, pH 7.5, 0.09% sodium azide, 0.01% BSA, 50% glycerol.
Immunogen
Synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-nr2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-nr2B antibody
Receptors for NMDA belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), including involvement in memory and learning processes. Several antagonists and agonists of NMDA receptors (NMDAR) have been identified, including the glutamate analogue Homoquinolinic acid, which displays a higher affinity for NR2B-containing NMDAR. Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage-dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease(4) and also epilepsy and ischemic neuronal cell death.
Product Categories/Family for anti-nr2B antibody
Applications Tested/Suitable for anti-nr2B antibody
Western Blot (WB)
Application Notes for anti-nr2B antibody
Suitable for use in Western Blot.
Dilution: Western Blot: 1:1000
NCBI/Uniprot data below describe general gene information for nr2B. It may not necessarily be applicable to this product.
NCBI GI #
UniProt Primary Accession #
Molecular Weight
35,476 Da[Similar Products]
NCBI Official Full Name
N-methyl D-aspartate receptor subunit 2B
UniProt Protein Name
N-methyl D-aspartate receptor subunit 2B
UniProt Gene Name
UniProt Entry Name
B5QTB1_9TELE
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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