P46721
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
organic anion transporting polypeptide 1 (OATP1)
NCBI Official Synonym Full Names
solute carrier organic anion transporter family, member 1A2
NCBI Protein Information
solute carrier organic anion transporter family member 1A2; OATP-1; OTTHUMP00000209604; OTTHUMP00000209605; solute carrier family 21 member 3; organic anion transporting polypeptide A; organic anion-transporting polypeptide 1; sodium-independent organic anion transporter; solute carrier family 21 (organic anion transporter), member 3
UniProt Protein Name
Solute carrier organic anion transporter family member 1A2
UniProt Synonym Protein Names
OATP-A; Organic anion-transporting polypeptide 1; OATP-1; Sodium-independent organic anion transporter; Solute carrier family 21 member 3
UniProt Synonym Gene Names
UniProt Entry Name
SO1A2_HUMAN
NCBI Summary for SLCO1A2
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
UniProt Comments for SLCO1A2
SLCO1A2: Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids. Selectively inhibited by the grapefruit juice component naringin. Belongs to the organo anion transporter (TC 2.A.60) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p12
Cellular Component: integral to membrane; plasma membrane
Molecular Function: organic anion transmembrane transporter activity
Biological Process: bile acid and bile salt transport; sodium-independent organic anion transport; bile acid metabolic process; transmembrane transport; organic anion transport
Research Articles on SLCO1A2
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Pathways associated with anti-SLCO1A2 antibody
Diseases associated with anti-SLCO1A2 antibody
Organs/Tissues associated with anti-SLCO1A2 antibody
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