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Pou4f1 recombinant protein :: POU domain, class 4, transcription factor 1 (Pou4f1) Recombinant Protein

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Catalog # MBS959303
Unit / Price
  0.05 mg (E-Coli)  /  $525 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $695 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $770 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $840 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $930 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,045 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,060 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,080 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,080 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,535 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,585 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,650 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,060 +2 FREE 8GB USB
Pou4f1 recombinant protein
Product Name

POU domain, class 4, transcription factor 1 (Pou4f1), Recombinant Protein

Also Known As

Recombinant Rat POU domain, class 4, transcription factor 1 (Pou4f1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-128aa, Full length protein
Sequence Length
336
Sequence
RRIKLGVTQA DVGSALANLK IPGVGSLSQS TICRFESLTL SHNNMIALKP ILQAWLEEAE GAQREKMNKP ELFNGGEKKR KRTSIAAPEK RSLEAYFAVQ PRPSSEKIAA IAEKLDLKKN VVRVWFCN
3D Structure
ModBase 3D Structure for P20266
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rat
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Pou4f1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Pou4f1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,068 Da
NCBI Official Full Name
LOW QUALITY PROTEIN: POU domain, class 4, transcription factor 1 isoform X1
NCBI Official Synonym Full Names
POU class 4 homeobox 1
NCBI Official Symbol
Pou4f1  [Similar Products]
NCBI Official Synonym Symbols
Brn3a; brn-3A
  [Similar Products]
NCBI Protein Information
POU domain, class 4, transcription factor 1; LOW QUALITY PROTEIN: POU domain, class 4, transcription factor 1
UniProt Protein Name
POU domain, class 4, transcription factor 1
UniProt Synonym Protein Names
Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A
UniProt Gene Name
Pou4f1  [Similar Products]
UniProt Synonym Gene Names
Brn-3; Brn3; Brn3a; Brain-3A; Brn-3A  [Similar Products]
NCBI Summary for Pou4f1
transcription factor containing the Pit1-Oct1-Unc86 (POU) domain; regulates expression of Trk receptors and Bcl-2 family members; associated with sensory neuron survival [RGD, Feb 2006]
UniProt Comments for Pou4f1
Multifunctional transcription factor with different regions mediating its different effects (PubMed:10640682). Acts by binding (via its C-terminal domain) to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Regulates the expression of specific genes involved in differentiation and survival within a subset of neuronal lineages (PubMed:11053412). It has been shown that activation of some of these genes requires its N-terminal domain, maybe through a neuronal-specific cofactor. Ativates BCL2 expression and protects neuronal cells from apoptosis (via the N-terminal domain). Induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. Exerts its major developmental effects in somatosensory neurons and in brainstem nuclei involved in motor control. Stimulates the binding affinity of the nuclear estrogene receptor ESR1 to DNA estrogen response element (ERE), and hence modulates ESR1-induced transcriptional activity. May positively regulate POU4F2 and POU4F3. Regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Plays a role in TNFSF11-mediated terminal osteoclast differentiation. Negatively regulates its own expression interacting directly with a highly conserved autoregulatory domain surrounding the transcription initiation site ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withPou4f1 recombinant protein
 Reference Product  PubMed Publications
 Pax3 recombinant protein  >2 publications with Pou4f1 and Pax3
Organs/Tissues associated with Pou4f1 recombinant protein
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