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PP recombinant protein :: infectious bursal disease virus Polyprotein Recombinant Protein

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Catalog # MBS1265131
Unit / Price
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  0.01 mg  /  $235 +1 FREE 8GB USB
  0.05 mg  /  $320 +1 FREE 8GB USB
  0.1 mg  /  $535 +1 FREE 8GB USB
  0.2 mg  /  $855 +1 FREE 8GB USB
  0.5 mg  /  $1,125 +1 FREE 8GB USB
  1 mg  /  $1,725 +2 FREE 8GB USB
SDS-PAGE
Product Name

infectious bursal disease virus Polyprotein (PP), Recombinant Protein

Popular Item
Full Product Name

Recombinant Avian infectious bursal disease virus Polyprotein

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
723-1012aa; Partial
Sequence
RFPHNPRDWD RLPYLNLPYL PPNAGRQYHL AMAASEFKET PELESAVRAM EAAANVDPLF QSALSVFMWL EENGIVTDMA NFALSDPNAH RMRNFLANAP QAGSKSQRAK YGTAGYGVEA RGPTPEEAQR EKDTRISKKM ETMGIYFATP EWVALNGHRG PSPGQLKYWQ NTREIPDPNE DYLDYVHAEK SRLASEEQIL RAATSIYGAP GQAEPPQAFI DEVAKVYEIN HGRGPNQEQM KDLLLTAMEM KHRNPRRALP KPKPKPNAPT QRPPGRLGRW IRTVSDEDLE
3D Structure
ModBase 3D Structure for P15480
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PP recombinant protein
Capsid protein VP2 self assbles to form an icosahedral capsid with a T=13 symmetry, about 70 nm in diameter, and consisting of 260 VP2 trimers. The capsid encapsulates the genomic dsRNA. VP2 is also involved in attachment and entry into the host cell by interacting with host ITGA4/ITGB1. The precursor of VP2 plays an important role in capsid assembly. First, pre-VP2 and VP2 oligomers assble to form a procapsid. Then, the pre-VP2 intermediates may be processed into VP2 proteins by proteolytic cleavage mediated by VP4 to obtain the mature virion. The final capsid is composed of pentamers and hexamers but VP2 has a natural tendency to assble into all-pentameric structures. Therefore pre-VP2 may be required to allow formation of the hexameric structures. Protease VP4 is a serine protease that cleaves the polyprotein into its final products. Pre-VP2 is first partially cleaved, and may be completely processed by VP4 upon capsid maturation.

PP recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for PP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
Molecular Weight
NCBI Official Full Name
Structural polyprotein
UniProt Protein Name
Structural polyprotein
UniProt Synonym Protein Names
Precursor of VP2; Pre-VP2
UniProt Gene Name
UniProt Synonym Gene Names
Pre-VP2; p1; p2; p3; p4; NS  [Similar Products]
UniProt Entry Name
POLS_IBDVC
UniProt Comments for PP
Capsid protein VP2 self assembles to form an icosahedral capsid with a T=13 symmetry, about 70 nm in diameter, and consisting of 260 VP2 trimers. The capsid encapsulates the genomic dsRNA. VP2 is also involved in attachment and entry into the host cell by interacting with host ITGA4/ITGB1 ().
Product References and Citations for PP recombinant protein
Nucleotide sequence of infectious bursal disease virus genome segment A delineates two major open reading frames.Spies U., Mueller H., Becht H.Nucleic Acids Res. 17:7982-7982(1989) A comparison of the sequences of segment A of four infectious bursal disease virus strains and identification of a variable region in VP2.Bayliss C.D., Spies U., Shaw K., Peters R.W., Papageorgiou A., Mueller H., Boursnell M.E.G.J. Gen. Virol. 71:1303-1312(1990) Role of Ser-652 and Lys-692 in the protease activity of infectious bursal disease virus VP4 and identification of its substrate cleavage sites.Lejal N., Da Costa B., Huet J.-C., Delmas B.J. Gen. Virol. 81:983-992(2000) The capsid of infectious bursal disease virus contains several small peptides arising from the maturation process of pVP2.Da Costa B., Chevalier C., Henry C., Huet J.-C., Petit S., Lepault J., Boot H., Delmas B.J. Virol. 76:2393-2402(2002) Structure of birnavirus-like particles determined by combined electron cryomicroscopy and X-ray crystallography.Pous J., Chevalier C., Ouldali M., Navaza J., Delmas B., Lepault J.J. Gen. Virol. 86:2339-2346(2005) The birnavirus crystal structure reveals structural relationships among icosahedral viruses.Coulibaly F., Chevalier C., Gutsche I., Pous J., Navaza J., Bressanelli S., Delmas B., Rey F.A.Cell 120:761-772(2005)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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