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PPP1R15A recombinant protein :: Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) Recombinant Protein

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Catalog # MBS1033254
Unit / Price
  0.01 mg (Yeast)  /  $135 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $255 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $420 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $665 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $1,060 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,090 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,235 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,430 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,485 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,565 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,580 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,725 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,230 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,235 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $2,245 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,930 +3 FREE 8GB USB
SDS-PAGE
Product Name

Protein phosphatase 1 regulatory subunit 15A (PPP1R15A), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS1033254 COA
Sequence Positions
40-674aa, Full Length of Mature Protein
Sequence Length
515
Sequence
GPLEPWLVEA VKGAALVEAG LEGEARTPLA IPHTPWGRRP EEEAEDSGGP GEDRETLGLK TSSSLPEAWG LLDDDDGMYG EREATSVPRG QGSQFADGQR APLSPSLLIR TLQGSDKNPG EEKAEEEGVA EEEGVNKFSY PPSHRECCPA VEEEDDEEAV KKEAHRTSTS ALSPGSKPST WVSCPGEEEN QATEDKRTER SKGARKTSVS PRSSGSDPRS WEYRSGEASE EKEEKAHKET GKGEAAPGPQ SSAPAQRPQL KSWWCQPSDE EEGEVKALGA AEKDGEAECP PCIPPPSAFL KAWVYWPGED TEEEEDEEED EDSDSGSDEE EGEAEASSST PATGVFLKSW VYQPGEDTEE EEDEDSDTGS AEDEREAETS ASTPPASAFL KAWVYRPGED TEEEEDEDVD SEDKEDDSEA ALGEAESDPH PSHPDQRAHF RGWGYRPGKE TEEEEAAEDW GEAEPCPFRV AIYVPGEKPP PPWAPPRLPL RLQRRLKRPE TPTHDPDPET PLKARKVRFS EKVTVHFLAV WAGPAQAARQ GPWEQLARDR SRFARRITQA QEELSPCLTP AARARAWARL RNPPLAPIPA LTQTLPSSSV PSSPVQTTPL SQAVATPSRS SAAAAAALDL SGRRG
OMIM
611048
3D Structure
ModBase 3D Structure for O75807
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of PPP1R15A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PPP1R15A recombinant protein
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

PPP1R15A recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for PPP1R15A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,515 Da
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 15A
NCBI Official Synonym Full Names
protein phosphatase 1 regulatory subunit 15A
NCBI Official Symbol
PPP1R15A  [Similar Products]
NCBI Official Synonym Symbols
GADD34
  [Similar Products]
NCBI Protein Information
protein phosphatase 1 regulatory subunit 15A
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 15A
UniProt Synonym Protein Names
Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homolog
UniProt Gene Name
PPP1R15A  [Similar Products]
UniProt Synonym Gene Names
GADD34  [Similar Products]
NCBI Summary for PPP1R15A
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]
UniProt Comments for PPP1R15A
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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