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PRG2 recombinant protein :: Bone marrow proteoglycan (PRG2) Recombinant Protein

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Catalog # MBS953649
Unit / Price
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  0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $510 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $680 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $835 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,050 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,055 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,070 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,520 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,635 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,040 +2 FREE 8GB USB
SDS-Page
Product Name

Bone marrow proteoglycan (PRG2), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Bone marrow proteoglycan (PRG2), partial

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS953649 COA
Sequence Positions
106-222aa, Full Length of Mature Protein
Sequence
TCRYLLVRSL QTFSQAWFTC RRCYRGNLVS IHNFNINYRI QCSVSALNQG QVWIGGRITG SGRCRRFQWV DGSRWNFAYW AAHQPWSRGG HCVALCTRGG HWRRAHCLRR LPFICSY
OMIM
605601
3D Structure
ModBase 3D Structure for P13727
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PRG2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PRG2purchase
A major human basic functional protein of eosinophil granule (s), human bone marrow proteoglycan PRG2, increases expression during pregnancy and experimental evidence demonstrates active enzymatic activity against parasitic infections caused by cell entry. However, mechanisms and potential target proteins is an open field.judging by cited Pubmed and PMC abstract database searches. MyBiosource is offering a gene and Uniprotkb protein sequence verified recombinant PRG basic protein for your research problems. Expressed in multiple system, HIS tagged and SDS-Page purified, we supply economical size ranges to meet any lab budget and needs from 0.1 mg for baculovirus or yeast system to 1 mg quantities for E coli or mammalian systems. All eosinophil major basic protein PRG2 is shipped with extensive href manual and all technical information you will need to extend your experiments. This product is available in US, Europe and worldwide.
Related Product Information for
PRG2 recombinant protein
This protein is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.

PRG2 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for PRG2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15.77kD
NCBI Official Full Name
bone marrow proteoglycan isoform 2 preproprotein
NCBI Official Synonym Full Names
proteoglycan 2, pro eosinophil major basic protein
NCBI Official Symbol
NCBI Official Synonym Symbols
MBP; BMPG; MBP1; proMBP
  [Similar Products]
NCBI Protein Information
bone marrow proteoglycan
UniProt Protein Name
Bone marrow proteoglycan
UniProt Synonym Protein Names
Proteoglycan 2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
MBP; BMPG; EMBP; MBP  [Similar Products]
NCBI Summary for PRG2
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
UniProt Comments for PRG2
Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with PRG2 recombinant protein
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