View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List INHBA active protein :: Activin A Active Protein Catalog # MBS506373 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Activin A (INHBA), Active Protein Popular Item Full Product Name Human/Mouse/Rat Activin A (AF) Product Synonym Names Inhibin beta-1; FRP; FSH-releasing protein Product Gene Name INHBA active protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 117-234 Sequence MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS OMIM 147290 3D Structure ModBase 3D Structure for P08476 Host E Coli Purity/Purification >=95% Form/Format Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) Species Human/Mouse/Rat Endotoxin <=1.00 EUs/ug; Kinetic LAL (50% confidence) Biological Activity ED50 <=10 ng/mL (>=1 x 10^5 units/mg); Cytotoxicity of MPC-11 Cells Monomer/Dimer Dimer Tag None Reconstitution Sterile water at 0.1 mg/mL International Units 1.2 IU/mug = (NIBSC 91/626) Animal Components This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols. Preparation and Storage 12 months from date of receipt when stored at -20 degree C to-80 degree C as supplied. 1 month when stored at 4 degree C after reconstituting as directed. 3 months when stored at -20 degree C to -80 degree C after reconstituting as directed. Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of INHBA active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for INHBA active protein Activin A is a member of the transforming growth factor beta (TGF-beta) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A is a homodimer comprised of two activin betaA chains. Cleavage of the N-terminal propeptide renders the activin protein biologically active. Human activin A shares 100% amino acid sequence identity with mouse, rat, porcine, bovine, and feline activin A proteins. GEL Data of INHBA active protein Biological Activity of INHBA active protein TOP NCBI/Uniprot data below describe general gene information for INHBA. It may not necessarily be applicable to this product. NCBI GI # 4504699 NCBI GeneID 3624 NCBI Accession # NP_002183.1 [Other Products] NCBI GenBank Nucleotide # NP_002183.1 [Other Products] UniProt Primary Accession # P08476 [Other Products] UniProt Related Accession # P08476[Other Products] Molecular Weight 13.1; 26.2[Similar Products] TOP NCBI Official Full Name inhibin beta A chain preproprotein NCBI Official Synonym Full Names inhibin subunit beta A NCBI Official Symbol INHBA [Similar Products] NCBI Official Synonym Symbols EDF; FRP [Similar Products] NCBI Protein Information inhibin beta A chain UniProt Protein Name Inhibin beta A chain UniProt Synonym Protein Names Activin beta-A chain; Erythroid differentiation protein Protein Family Inhibin UniProt Gene Name INHBA [Similar Products] UniProt Synonym Gene Names EDF [Similar Products] UniProt Entry Name INHBA_HUMAN TOP NCBI Summary for INHBA This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016] TOP Research Articles on INHBA 1. It was indicated that concentrations of activin A in serum and synovial fluid showed a positive correlation with the occurrence and severity of knee osteoarthritis. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with INHBA active protein Reference Product PubMed Publications INHBB active protein >21 publications with INHBA and INHBB INHA active protein >15 publications with INHBA and INHA FST active protein >9 publications with INHBA and FST FSTL3 active protein >3 publications with INHBA and FSTL3 FSHB active protein >1 publications with INHBA and FSHB INHBC active protein >1 publications with INHBA and INHBC ACVR2B active protein >1 publications with INHBA and ACVR2B Pathways associated with INHBA active protein Products by Pathway Pathway Diagram ALK1 Signaling Events Pathway antibodies ALK1 Signaling Events Pathway Diagram Antagonism Of Activin By Follistatin Pathway antibodies Antagonism Of Activin By Follistatin Pathway Diagram Cardiac Progenitor Differentiation Pathway antibodies Cardiac Progenitor Differentiation Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Glycoprotein Hormones Pathway antibodies Glycoprotein Hormones Pathway Diagram Integrated Pancreatic Cancer Pathway antibodies Integrated Pancreatic Cancer Pathway Diagram Metabolism Of Proteins Pathway antibodies Metabolism Of Proteins Pathway Diagram Peptide Hormone Biosynthesis Pathway antibodies Peptide Hormone Biosynthesis Pathway Diagram Peptide Hormone Metabolism Pathway antibodies Peptide Hormone Metabolism Pathway Diagram Diseases associated with INHBA active protein Disease Name Pubmed Publications Neoplasms Antibodies >22 publications with INHBA and Neoplasms Necrosis Antibodies >6 publications with INHBA and Necrosis Adenocarcinoma Antibodies >6 publications with INHBA and Adenocarcinoma Disease Models, Animal Antibodies >5 publications with INHBA and Disease Models, Animal Kidney Diseases Antibodies >4 publications with INHBA and Kidney Diseases Lung Neoplasms Antibodies >3 publications with INHBA and Lung Neoplasms Inflammation Antibodies >3 publications with INHBA and Inflammation Cardiovascular Diseases Antibodies >2 publications with INHBA and Cardiovascular Diseases Pancreatic Neoplasms Antibodies >2 publications with INHBA and Pancreatic Neoplasms Drug Toxicity Antibodies >2 publications with INHBA and Drug Toxicity Organs/Tissues associated with INHBA active protein Organ/Tissue Name Pubmed Publications Ovary Antibodies >22 publications with INHBA and Ovary Bone Antibodies >15 publications with INHBA and Bone Blood Antibodies >13 publications with INHBA and Blood Lung Antibodies >6 publications with INHBA and Lung Skin Antibodies >5 publications with INHBA and Skin Kidney Antibodies >5 publications with INHBA and Kidney Brain Antibodies >5 publications with INHBA and Brain Stomach Antibodies >5 publications with INHBA and Stomach Placenta Antibodies >5 publications with INHBA and Placenta Liver Antibodies >4 publications with INHBA and Liver TOP © 2006-24 MyBioSource.com. 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