Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Active Protein rightarrow CXCL13  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CEP55 cDNA Clone
 • Semaphorin 3A (SEMA3A) ELISA Kit
 • 2-Arachidonoylglycerol (2-AG) ELISA Kit
 • BAP1 Antibody
 • Tissue Inhibitors Of Metalloproteinase 1 (TIMP-1) ELISA Kit
 • COL1A2 Antibody
 • Zonulin (ZUN) ELISA Kit
 • Flt1, ED (Fzd1) Antibody
 • NDFIP1 Antibody
 • MAP2K2 Antibody
 • eIF4E-BP1 Recombinant Protein
 • A-kinase anchor protein SPHKAP (Sphkap) Recombinant Protein
 • Neutrophil Gelatinase Associated Lipocalin-Lipocalin-2 (NGAL... ELISA Kit
 • CASP2 and RIPK1 domain containing adaptor with death domain ... ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CXCL13 active protein :: C-X-C motif chemokine 13 protein (CXCL13) Active Protein

Scan QR to view Datasheet Catalog #    MBS969195
SDS-PAGE
Unit / Price
0.005 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $430 +1 FREE 8GB USB
0.25 mg  /  $725 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-X-C motif chemokine 13 protein (CXCL13), Active Protein

★Popular Item★
 Also Known As   

Recombinant Human C-X-C motif chemokine 13 protein (CXCL13) (Active)

 Product Synonym Names    Angie; BCA-1; B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13
 Product Gene Name   

CXCL13 active protein

[Similar Products]
 Product Synonym Gene Name    BCA1; BLC; SCYB13 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    23-109aa, Full Length of Mature Protein
 Sequence    VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP
 OMIM    AF044197 mRNA
 3D Structure    ModBase 3D Structure for O43927
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    >=97% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Lyophilized
Section Bar
 Species    Homo sapiens (Human)
 Biological Activity    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human B cells is in a concentration range of 1.0-10 ng/ml.
 Storage Buffer    0.2 um filtered PBS, pH 7.4,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
 Protein Note    Protein will be provided with aseptic processing and endotoxin removal.
Section Bar
 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Active Protein Note    Refer to the datasheet for activity details. For other activity applications, researchers should evaluate this protein for suitability in their model system.
 Other Notes    Small volumes of CXCL13 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for CXCL13 active protein

   Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.
 Product Categories/Family for CXCL13 active protein    Biological Active Protein; Immunology; Chemokine
Section Bar
 SDS-PAGE of CXCL13 active protein    CXCL13 active protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CXCL13. It may not necessarily be applicable to this product.
 NCBI GI #    5453577
 NCBI GeneID    10563
 NCBI Accession #    NP_006410.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006419.2 [Other Products]
Section Bar
 UniProt Primary Accession #    O43927 [Other Products]
 UniProt Related Accession #    O43927 [Other Products]
 Molecular Weight    10.3 kDa
Table BarTOPTable Bar
 NCBI Official Full Name    C-X-C motif chemokine 13
 NCBI Official Synonym Full Names    C-X-C motif chemokine ligand 13
 NCBI Official Symbol    CXCL13 [Similar Products]
 NCBI Official Synonym Symbols   
BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 13
 UniProt Protein Name    C-X-C motif chemokine 13
 UniProt Synonym Protein Names   
Angie; B cell-attracting chemokine 1; BCA-1; B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13
 Protein Family    C-X-C motif chemokine
 UniProt Gene Name    CXCL13 [Similar Products]
 UniProt Synonym Gene Names    BCA1; BLC; SCYB13; BCA-1 [Similar Products]
Section Bar
 NCBI Summary for CXCL13    B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Oct 2014]
Section Bar
 UniProt Comments for CXCL13    CXCL13: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: extracellular region; extracellular space

Molecular Function: CCR10 chemokine receptor binding; chemokine activity; CXCR3 chemokine receptor binding; CXCR5 chemokine receptor binding; fibroblast growth factor binding; heparin binding; protein heterodimerization activity; receptor agonist activity

Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; defense response to bacterium; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; lymphocyte chemotaxis across high endothelial venule; positive regulation of cell-cell adhesion mediated by integrin; positive regulation of integrin activation; regulation of cell proliferation; response to lipopolysaccharide
Table BarTOPTable Bar
 Research Articles on CXCL13    1. High CXCL13 expression is associated with B-cell Lymphoma.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with CXCL13 active proteinPathways associated with CXCL13 active protein
 Reference Product  PubMed Publications
 CXCR5 active protein  >212 publications with CXCL13 and CXCR5
 CXCL12 active protein  >137 publications with CXCL13 and CXCL12
 CCL21 active protein  >129 publications with CXCL13 and CCL21
 CCL19 active protein  >105 publications with CXCL13 and CCL19
 CXCL10 active protein  >57 publications with CXCL13 and CXCL10
 CCR7 active protein  >56 publications with CXCL13 and CCR7
 CXCL9 active protein  >35 publications with CXCL13 and CXCL9
 CXCR3 active protein  >30 publications with CXCL13 and CXCR3
 CCL25 active protein  >14 publications with CXCL13 and CCL25
 CCR10 active protein  >2 publications with CXCL13 and CCR10
 Products by Pathway  Pathway Diagram
 CXCR3-mediated Signaling Events Pathway antibodies  CXCR3-mediated Signaling Events Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Diseases associated with CXCL13 active proteinOrgans/Tissues associated with CXCL13 active protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >185 publications with CXCL13 and Inflammation
 Necrosis Antibodies  >67 publications with CXCL13 and Necrosis
 Disease Models, Animal Antibodies  >60 publications with CXCL13 and Disease Models, Animal
 Carcinoma Antibodies  >35 publications with CXCL13 and Carcinoma
 Brain Diseases Antibodies  >35 publications with CXCL13 and Brain Diseases
 Lung Diseases Antibodies  >35 publications with CXCL13 and Lung Diseases
 Vascular Diseases Antibodies  >24 publications with CXCL13 and Vascular Diseases
 Hyperplasia Antibodies  >20 publications with CXCL13 and Hyperplasia
 Kidney Diseases Antibodies  >20 publications with CXCL13 and Kidney Diseases
 Recurrence Antibodies  >18 publications with CXCL13 and Recurrence
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >192 publications with CXCL13 and Lymph Node
 Spleen Antibodies  >85 publications with CXCL13 and Spleen
 Bone Antibodies  >76 publications with CXCL13 and Bone
 Vascular Antibodies  >74 publications with CXCL13 and Vascular
 Lung Antibodies  >49 publications with CXCL13 and Lung
 Kidney Antibodies  >28 publications with CXCL13 and Kidney
 Intestine Antibodies  >23 publications with CXCL13 and Intestine
 Muscle Antibodies  >23 publications with CXCL13 and Muscle
 Prostate Antibodies  >20 publications with CXCL13 and Prostate
 Pharynx Antibodies  >20 publications with CXCL13 and Pharynx
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions