View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List EGF active protein :: Epidermal Growth Factor Active Protein Catalog # MBS506116 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Epidermal Growth Factor (EGF), Active Protein Popular Item Full Product Name Animal-Free Human EGF Product Synonym Names Urogastrone; URG Product Gene Name EGF active protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence NSDSECPLSH Â DGYCLHDGV CÂ MYIEALDK YAÂ CNCVVGY IGEÂ RCQYRD LKWWÂ ELR OMIM gene 611718 3D Structure ModBase 3D Structure for P01133 Host E Coli Purity/Purification >=95% Form/Format Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) Species Human Endotoxin <=1.00 EUs/ug; Kinetic LAL (50% confidence) Biological Activity ED50 <=100 pg/mL (>=1 x 10^7 units/mg) (Typical ED50 is 10-50 pg/mL); 3T3 Cell Proliferation Monomer/Dimer Monomer Tag None Reconstitution Sterile water at 0.1 mg/mL International Units 1.3 x 10^3 IUs/ug (NIBSC code 91/530) Animal Components This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols. Preparation and Storage 12 months from date of receipt when stored at -20 degree C to-80 degree C as supplied. 1 month when stored at 4 degree C after reconstituting as directed. 3 months when stored at -20 degree C to -80 degree C after reconstituting as directed. Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of EGF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for EGF active protein Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR). EGF is overexpressed in multiple tumor cell lines and promotes resistance to chemotherapy and radiation treatments. GEL Data of EGF active protein Biological Activity of EGF active protein TOP NCBI/Uniprot data below describe general gene information for EGF. It may not necessarily be applicable to this product. NCBI GI # 251757262 NCBI GeneID 1950 NCBI Accession # P01133.2 [Other Products] UniProt Primary Accession # P01133 [Other Products] UniProt Related Accession # P01133[Other Products] Molecular Weight 6.2 TOP NCBI Official Full Name Pro-epidermal growth factor NCBI Official Synonym Full Names epidermal growth factor NCBI Official Symbol EGF [Similar Products] NCBI Official Synonym Symbols URG; HOMG4 [Similar Products] NCBI Protein Information pro-epidermal growth factor UniProt Protein Name Pro-epidermal growth factor UniProt Synonym Protein Names Urogastrone Protein Family Epidermal growth factor UniProt Gene Name EGF [Similar Products] UniProt Synonym Gene Names EGF [Similar Products] UniProt Entry Name EGF_HUMAN TOP NCBI Summary for EGF This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] TOP Research Articles on EGF 1. Study found that urinary EGF/creatinine (uEGF/Cr) decreases with age in pediatric patients with Alport syndrome with a significantly faster rate than in healthy children of the same age. uEGF/Cr is significantly correlated with estimated glomerular filtration rate after adjustment for age, suggesting that uEGF/Cr is a promising biomarker for accelerated kidney function decline in pediatric patients with Alport syndrome. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with EGF active protein Reference Product PubMed Publications EGFR active protein >5653 publications with EGF and EGFR ERBB2 active protein >1352 publications with EGF and ERBB2 SRC active protein >1234 publications with EGF and SRC ERBB4 active protein >406 publications with EGF and ERBB4 GRB2 active protein >362 publications with EGF and GRB2 STAT3 active protein >295 publications with EGF and STAT3 ERBB3 active protein >275 publications with EGF and ERBB3 ADAM17 active protein >115 publications with EGF and ADAM17 FN1 active protein >8 publications with EGF and FN1 Pathways associated with EGF active protein Products by Pathway Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Arf6 Signaling Events Pathway antibodies Arf6 Signaling Events Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Ceramide Signaling Pathway antibodies Ceramide Signaling Pathway Diagram Choline Metabolism In Cancer Pathway antibodies Choline Metabolism In Cancer Pathway Diagram Choline Metabolism In Cancer Pathway antibodies Choline Metabolism In Cancer Pathway Diagram Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram Constitutive Signaling By EGFRvIII Pathway antibodies Constitutive Signaling By EGFRvIII Pathway Diagram Constitutive Signaling By Ligand-Responsive EGFR Cancer Variants Pathway antibodies Constitutive Signaling By Ligand-Responsive EGFR Cancer Variants Pathway Diagram Diseases associated with EGF active protein Disease Name Pubmed Publications Breast Neoplasms Antibodies >1679 publications with EGF and Breast Neoplasms Adenocarcinoma Antibodies >1324 publications with EGF and Adenocarcinoma Necrosis Antibodies >1005 publications with EGF and Necrosis Neoplasms, Experimental Antibodies >891 publications with EGF and Neoplasms, Experimental Cell Transformation, Neoplastic Antibodies >875 publications with EGF and Cell Transformation, Neoplastic Lung Neoplasms Antibodies >850 publications with EGF and Lung Neoplasms Inflammation Antibodies >734 publications with EGF and Inflammation Neoplasm Metastasis Antibodies >641 publications with EGF and Neoplasm Metastasis Liver Diseases Antibodies >574 publications with EGF and Liver Diseases Neoplasm Invasiveness Antibodies >554 publications with EGF and Neoplasm Invasiveness Organs/Tissues associated with EGF active protein Organ/Tissue Name Pubmed Publications Brain Antibodies >1875 publications with EGF and Brain Lung Antibodies >1810 publications with EGF and Lung Kidney Antibodies >1615 publications with EGF and Kidney Skin Antibodies >1429 publications with EGF and Skin Muscle Antibodies >1343 publications with EGF and Muscle Embryonic Tissue Antibodies >1128 publications with EGF and Embryonic Tissue Eye Antibodies >927 publications with EGF and Eye Intestine Antibodies >909 publications with EGF and Intestine Mouth Antibodies >872 publications with EGF and Mouth Placenta Antibodies >468 publications with EGF and Placenta TOP © 2006-24 MyBioSource.com. 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