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Exendin-4 Active Protein

Scan QR to view Datasheet Catalog #    MBS969141
SDS-PAGE
Unit / Price
0.02 mg  /  $115 +1 FREE 8GB USB
0.1 mg  /  $205 +1 FREE 8GB USB
0.25 mg  /  $220 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Exendin-4, Active Protein

★Popular Item★
 Also Known As   

Recombinant Heloderma suspectum Exendin-4

 Product Synonym Names    INN: Exenatide
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS969141 COA    COA PDF
 Sequence Positions    48-86. Full length of the mature protein.
 Sequence    HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS
 3D Structure    ModBase 3D Structure for P26349
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 Host    E Coli
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 Purity/Purification    >=96% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Lyophilized
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 Species    Heloderma suspectum (Gila monster)
 Biological Activity    1. Regulates Glucose levels rapidly; 2. Reduces Insulin resistance; 3. Reduces Glucagon; 4. Reduces HbA1c; 5. Stimulates beta cell growth which stimulates insulin production.
 Storage Buffer    0.2 um filtered 20 mM PB, pH 7.4, 150mM NaCl,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
 Protein Note    Protein will be provided with aseptic processing and endotoxin removal.
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 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Active Protein Note    Refer to the datasheet for activity details. For other activity applications, researchers should evaluate this protein for suitability in their model system.
 Other Notes    Small volumes of Exendin-4 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Exendin-4 active protein

   Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.
 Product Categories/Family for Exendin-4 active protein    Neuroscience 
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 SDS-PAGE of Exendin-4 active protein    Exendin-4 active protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Exendin-4. It may not necessarily be applicable to this product.
 NCBI GI #    2851623
 NCBI Accession #    P26349.2 [Other Products]
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 UniProt Primary Accession #    P26349 [Other Products]
 Molecular Weight    4.2 kDa [Similar Products]
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 NCBI Official Full Name    Exendin-4
 UniProt Protein Name    Exendin-4
 UniProt Synonym Protein Names   
INN: Exenatide
 Protein Family    Exendin
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 UniProt Comments for Exendin-4    Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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