NP_038546.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
fibroblast growth factor 9
NCBI Official Synonym Full Names
fibroblast growth factor 9
NCBI Official Synonym Symbols
NCBI Protein Information
fibroblast growth factor 9
UniProt Protein Name
Fibroblast growth factor 9
UniProt Synonym Protein Names
Glia-activating factor; GAF; HBGF-9
UniProt Synonym Gene Names
UniProt Entry Name
FGF9_MOUSE
UniProt Comments for FGF-9
FGF9: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3). Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness. Belongs to the heparin-binding growth factors family.
Protein type: Cytokine
Cellular Component: extracellular space; cell; cytoplasm; extracellular region; basement membrane; intracellular
Molecular Function: heparin binding; growth factor activity; fibroblast growth factor receptor binding; receptor binding
Biological Process: negative regulation of Wnt receptor signaling pathway; positive regulation of transcription, DNA-dependent; multicellular organismal development; embryonic skeletal development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of activin receptor signaling pathway; positive regulation of MAPKKK cascade; cell-cell signaling; protein import into nucleus; male sex determination; positive regulation of cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of smoothened signaling pathway; chondrocyte differentiation; angiogenesis; cell differentiation; regulation of timing of cell differentiation; embryonic gut development; positive regulation of cardiac muscle cell proliferation; embryonic limb morphogenesis; inner ear morphogenesis; fibroblast growth factor receptor signaling pathway; male gonad development; osteoblast differentiation; positive regulation of cell division; positive regulation of epithelial cell proliferation; lung development
Research Articles on FGF-9
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Pathways associated with FGF-9 active protein
Diseases associated with FGF-9 active protein
Organs/Tissues associated with FGF-9 active protein
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