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IFNA2 active protein :: Interferon alpha-2 protein (IFNA2) Active Protein

Scan QR to view Datasheet Catalog #    MBS969394
SDS-PAGE
Unit / Price
0.02 mg  /  $115 +1 FREE 8GB USB
0.1 mg  /  $205 +1 FREE 8GB USB
0.25 mg  /  $260 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interferon alpha-2 protein (IFNA2), Active Protein

★Popular Item★
 Also Known As   

Recombinant Human Interferon alpha-2 protein (IFNA2) (Active)

 Product Synonym Names    IFN-alpha-2; LeIF A
 Product Gene Name   

IFNA2 active protein

[Similar Products]
 Product Synonym Gene Name    IFNA2A; IFNA2B; IFNA2C [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    24-188aa, Full Length of Mature Protein
 Sequence    CDLPQTHSLG SRRTLMLLAQ MRKISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE
 OMIM    J00207 Genomic DNA
 3D Structure    ModBase 3D Structure for P01563
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 Host    E Coli
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 Purity/Purification    >=97% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Lyophilized
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 Species    Homo sapiens (Human)
 Biological Activity    Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 1.0 108 IU/mg.
 Storage Buffer    0.2 um filtered PBS, pH 7.4,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
 Protein Note    Protein will be provided with aseptic processing and endotoxin removal.
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 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Active Protein Note    Refer to the datasheet for activity details. For other activity applications, researchers should evaluate this protein for suitability in their model system.
 Other Notes    Small volumes of IFNA2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IFNA2 active protein

   Produced by macrophages, IFN-alpha have antiviral activities.
 Product Categories/Family for IFNA2 active protein    Biological Active Protein; Immunology; Tumor Necrosis Factor
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 SDS-PAGE of IFNA2 active protein    IFNA2 active protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for IFNA2. It may not necessarily be applicable to this product.
 NCBI GI #    11067751
 NCBI GeneID    3440
 NCBI Accession #    NP_000596.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000605.3 [Other Products]
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 UniProt Primary Accession #    P01563 [Other Products]
 UniProt Secondary Accession #    P01564; Q14606; Q6DJX8; Q96KI6; H2DF54; H2DF55 [Other Products]
 UniProt Related Accession #    P01563 [Other Products]
 Molecular Weight    19.2 kDa
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 NCBI Official Full Name    interferon alpha-2
 NCBI Official Synonym Full Names    interferon alpha 2
 NCBI Official Symbol    IFNA2 [Similar Products]
 NCBI Official Synonym Symbols   
IFNA; INFA2; IFNA2B; IFN-alphaA
[Similar Products]
 NCBI Protein Information    interferon alpha-2
 UniProt Protein Name    Interferon alpha-2
 UniProt Synonym Protein Names   
Interferon alpha-A; LeIF A
 UniProt Gene Name    IFNA2 [Similar Products]
 UniProt Synonym Gene Names    IFNA2A; IFNA2B; IFNA2C; IFN-alpha-2; LeIF A [Similar Products]
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 NCBI Summary for IFNA2    This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
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 UniProt Comments for IFNA2    IFNA2: Produced by macrophages, IFN-alpha have antiviral activities. Belongs to the alpha/beta interferon family.

Protein type: Membrane protein, integral; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p21.3

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; interferon-alpha/beta receptor binding; protein binding

Biological Process: apoptosis; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor linked signal transduction; cell-cell signaling; cytokine and chemokine mediated signaling pathway; defense response to virus; humoral immune response; inflammatory response; innate immune response; natural killer cell activation during immune response; negative regulation of T cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of virion penetration into host cell; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of phosphorylation; positive regulation of transcription, DNA-dependent; positive regulation of tyrosine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response
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 Research Articles on IFNA2    1. Interferon-alpha-induced CD100 expression on naive CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IFNA2 active proteinPathways associated with IFNA2 active protein
 Reference Product  PubMed Publications
 IFNAR2 active protein  >3 publications with IFNA2 and IFNAR2
 IFNG active protein  >2 publications with IFNA2 and IFNG
 STAT2 active protein  >2 publications with IFNA2 and STAT2
 IFNAR1 active protein  >2 publications with IFNA2 and IFNAR1
 IRF1 active protein  >1 publications with IFNA2 and IRF1
 Products by Pathway  Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Hepatitis B Pathway antibodies  Hepatitis B Pathway Diagram
Diseases associated with IFNA2 active protein
 Disease Name  Pubmed Publications
 Carcinoma, Renal Cell Antibodies  >1 publications with IFNA2 and Carcinoma, Renal Cell
 Skin Diseases Antibodies  >1 publications with IFNA2 and Skin Diseases
 Anemia Antibodies  >1 publications with IFNA2 and Anemia
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