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Scgb1a1 active protein :: Uteroglobin protein (Scgb1a1) Active Protein

Scan QR to view Datasheet Catalog #    MBS969174 Scgb1a1 active protein
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.05 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $250 +1 FREE 8GB USB
0.25 mg  /  $380 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Uteroglobin protein (Scgb1a1), Active Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Uteroglobin protein (Scgb1a1) (Active)

 Product Synonym Names    Clara cell 17 kDa protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein
 Product Gene Name   

Scgb1a1 active protein

[Similar Products]
 Product Synonym Gene Name    Cc10; Ugb; Utg [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    22-96aa, Full Length of Mature Protein
 Sequence    DICPGFLQVL EALLMESESG YVASLKPFNP GSDLQNAGTQ LKRLVDTLPQ ETRINIMKLT EKILTSPLCK QDLRF
 3D Structure    ModBase 3D Structure for Q06318
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 Host    E Coli
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 Purity/Purification    >=98% as determined by SDS-PAGE and HPLC. (lot specific)
 Form/Format    Lyophilized
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 Species    Mus musculus (Mouse)
 Biological Activity    Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 ug/ml, corresponding to a specific activity of > 200 IU/m.
 Storage Buffer    0.2 um filtered 20 mM PB, pH 7.4, 150mM NaCl,lyophilized
 Endotoxin    Less than 1.0 EU/ug as determined by LAL method.
 Protein Note    Protein will be provided with aseptic processing and endotoxin removal.
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 Preparation and Storage    Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Active Protein Note    Refer to the datasheet for activity details. For other activity applications, researchers should evaluate this protein for suitability in their model system.
 Other Notes    Small volumes of Scgb1a1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Scgb1a1 active protein

   Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
 Product Categories/Family for Scgb1a1 active protein    Biological Active Protein; Immunology
NCBI/Uniprot data below describe general gene information for Scgb1a1. It may not necessarily be applicable to this product.
 NCBI GI #    6755947
 NCBI GeneID    22287
 NCBI Accession #    NP_035811.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011681.2 [Other Products]
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 UniProt Primary Accession #    Q06318 [Other Products]
 UniProt Related Accession #    Q06318 [Other Products]
 Molecular Weight    16.7 kDa
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 NCBI Official Full Name    uteroglobin
 NCBI Official Synonym Full Names    secretoglobin, family 1A, member 1 (uteroglobin)
 NCBI Official Symbol    Scgb1a1 [Similar Products]
 NCBI Official Synonym Symbols   
UG; UGB; Utg; CC10; CC16; CCSP; PCB-BP
[Similar Products]
 NCBI Protein Information    uteroglobin
 UniProt Protein Name    Uteroglobin
 UniProt Synonym Protein Names   
Clara cell 17 kDa protein; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1
 Protein Family    Uteroglobin
 UniProt Gene Name    Scgb1a1 [Similar Products]
 UniProt Synonym Gene Names    Cc10; Ugb; Utg; CCPBP; CC10 [Similar Products]
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 UniProt Comments for Scgb1a1    SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family.

Protein type: Cell cycle regulation; Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19|19 A

Cellular Component: cytoplasm; endoplasmic reticulum; extracellular space; intracellular; nuclear envelope; rough endoplasmic reticulum; secretory granule

Biological Process: negative regulation of interferon-gamma production; negative regulation of interleukin-13 production; negative regulation of interleukin-4 production; negative regulation of interleukin-5 production; negative regulation of T cell proliferation; negative regulation of transcription from RNA polymerase II promoter; regulation of inflammatory response; regulation of mRNA stability; response to cytokine stimulus
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 Research Articles on Scgb1a1    1. Chronic P. aeruginosa inflammation resulted in chronic bronchitis and emphysematous changes in CCSP-deficient mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Scgb1a1 active proteinPathways associated with Scgb1a1 active protein
 Reference Product  PubMed Publications
 Tnf active protein  >24 publications with Scgb1a1 and Tnf
 Sftpc active protein  >21 publications with Scgb1a1 and Sftpc
 Foxa2 active protein  >11 publications with Scgb1a1 and Foxa2
 Foxa1 active protein  >10 publications with Scgb1a1 and Foxa1
 Nkx2-1 active protein  >9 publications with Scgb1a1 and Nkx2-1
 Scgb3a2 active protein  >7 publications with Scgb1a1 and Scgb3a2
 Adss active protein  >3 publications with Scgb1a1 and Adss
 Spdef active protein  >2 publications with Scgb1a1 and Spdef
 Sftpa1 active protein  >2 publications with Scgb1a1 and Sftpa1
 Sftpb active protein  >1 publications with Scgb1a1 and Sftpb
 Products by Pathway  Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram
Diseases associated with Scgb1a1 active proteinOrgans/Tissues associated with Scgb1a1 active protein
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >309 publications with Scgb1a1 and Lung Diseases
 Inflammation Antibodies  >148 publications with Scgb1a1 and Inflammation
 Lung Injury Antibodies  >137 publications with Scgb1a1 and Lung Injury
 Asthma Antibodies  >81 publications with Scgb1a1 and Asthma
 Lung Neoplasms Antibodies  >59 publications with Scgb1a1 and Lung Neoplasms
 Fibrosis Antibodies  >47 publications with Scgb1a1 and Fibrosis
 Carcinoma Antibodies  >43 publications with Scgb1a1 and Carcinoma
 Respiration Disorders Antibodies  >41 publications with Scgb1a1 and Respiration Disorders
 Pneumonia Antibodies  >40 publications with Scgb1a1 and Pneumonia
 Necrosis Antibodies  >35 publications with Scgb1a1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >493 publications with Scgb1a1 and Lung
 Embryonic Tissue Antibodies  >22 publications with Scgb1a1 and Embryonic Tissue
 Heart Antibodies  >17 publications with Scgb1a1 and Heart
 Uterus Antibodies  >16 publications with Scgb1a1 and Uterus
 Muscle Antibodies  >12 publications with Scgb1a1 and Muscle
 Liver Antibodies  >9 publications with Scgb1a1 and Liver
 Intestine Antibodies  >7 publications with Scgb1a1 and Intestine
 Tongue Antibodies  >4 publications with Scgb1a1 and Tongue
 Pancreas Antibodies  >3 publications with Scgb1a1 and Pancreas
 Stomach Antibodies  >1 publications with Scgb1a1 and Stomach
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