NP_004053.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
85,774 Da
NCBI Official Full Name
cadherin-16 isoform 1
NCBI Official Synonym Full Names
cadherin 16
NCBI Protein Information
cadherin-16
UniProt Protein Name
Cadherin-16
UniProt Synonym Protein Names
Kidney-specific cadherin; Ksp-cadherin
UniProt Synonym Gene Names
NCBI Summary for CDH16
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
UniProt Comments for CDH16
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Research Articles on CDH16
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Products associated with CDH16 antibody pair kit
Diseases associated with CDH16 antibody pair kit
Organs/Tissues associated with CDH16 antibody pair kit
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