AAC98318.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,776 Da
NCBI Official Full Name
glutaredoxin
NCBI Official Synonym Full Names
glutaredoxin
NCBI Official Synonym Symbols
NCBI Protein Information
glutaredoxin-1
UniProt Protein Name
Glutaredoxin-1
UniProt Synonym Protein Names
Thioltransferase-1; TTase-1
UniProt Synonym Gene Names
NCBI Summary for GLRX
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
UniProt Comments for GLRX
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Research Articles on GLRX
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Products associated with GLRX antibody pair kit
Pathways associated with GLRX antibody pair kit
Diseases associated with GLRX antibody pair kit
Organs/Tissues associated with GLRX antibody pair kit
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