AAB47721.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
66,039 Da
NCBI Official Full Name
keratin 1
NCBI Official Synonym Full Names
keratin 1
NCBI Official Synonym Symbols
K1; CK1; EHK; EHK1; EPPK; KRT1A; NEPPK [Similar Products]
NCBI Protein Information
keratin, type II cytoskeletal 1
UniProt Protein Name
Keratin, type II cytoskeletal 1
UniProt Synonym Protein Names
67 kDa cytokeratin; Cytokeratin-1; CK-1; Hair alpha protein; Keratin-1; K1; Type-II keratin Kb1
UniProt Synonym Gene Names
NCBI Summary for KRT1
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT1
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
Research Articles on KRT1
Precautions
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Disclaimer
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Products associated with KRT1 antibody pair kit
Pathways associated with KRT1 antibody pair kit
Diseases associated with KRT1 antibody pair kit
Disease Name |
Pubmed Publications |
Skin Neoplasms Antibodies |
>51 publications with KRT1 and Skin Neoplasms |
Hyperkeratosis, Epidermolytic Antibodies |
>50 publications with KRT1 and Hyperkeratosis, Epidermolytic |
Inflammation Antibodies |
>38 publications with KRT1 and Inflammation |
Carcinoma, Squamous Cell Antibodies |
>29 publications with KRT1 and Carcinoma, Squamous Cell |
Hyperplasia Antibodies |
>26 publications with KRT1 and Hyperplasia |
Immune System Diseases Antibodies |
>25 publications with KRT1 and Immune System Diseases |
Keratoderma, Palmoplantar, Epidermolytic Antibodies |
>24 publications with KRT1 and Keratoderma, Palmoplantar, Epidermolytic |
Necrosis Antibodies |
>13 publications with KRT1 and Necrosis |
Cell Transformation, Neoplastic Antibodies |
>12 publications with KRT1 and Cell Transformation, Neoplastic |
Lung Diseases Antibodies |
>10 publications with KRT1 and Lung Diseases |
Organs/Tissues associated with KRT1 antibody pair kit
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