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anti-YWHAZ antibody :: Rabbit 14-3-3 zeta/delta (Phospho-Thr232) Antibody

Scan QR to view Datasheet Catalog #    MBS004464 anti-YWHAZ antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3 zeta/delta (Phospho-Thr232) (YWHAZ), Antibody

 Also Known As   

Rabbit 14-3-3 zeta/delta (Phospho-Thr232) Antibody

 Product Gene Name   

anti-YWHAZ antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 8; NC_000008.10 (101930804..101965623, complement). Location: 8q23.1
 OMIM    601288
 3D Structure    ModBase 3D Structure for P63104
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-YWHAZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-YWHAZ antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for YWHAZ. It may not necessarily be applicable to this product.
 NCBI GI #    208973238
 NCBI GeneID    7534
 NCBI Accession #    NP_001129171.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001135699.1 [Other Products]
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 UniProt Primary Accession #    P63104 [Other Products]
 UniProt Secondary Accession #    P29213; P29312; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33; A8K1N0 [Other Products]
 UniProt Related Accession #    P63104 [Other Products]
 Molecular Weight    27,745 Da [Similar Products]
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 NCBI Official Full Name    14-3-3 protein zeta/delta
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
 NCBI Official Symbol    YWHAZ [Similar Products]
 NCBI Official Synonym Symbols   
YWHAD; KCIP-1; 14-3-3-zeta
[Similar Products]
 NCBI Protein Information    14-3-3 protein zeta/delta; 14-3-3 zeta; 14-3-3 delta; phospholipase A2; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; 14-3-3 protein/cytosolic phospholipase A2; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
 UniProt Protein Name    14-3-3 protein zeta/delta
 UniProt Synonym Protein Names   
Protein kinase C inhibitor protein 1
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAZ [Similar Products]
 UniProt Synonym Gene Names    KCIP-1 [Similar Products]
 UniProt Entry Name    1433Z_HUMAN
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 NCBI Summary for YWHAZ    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]
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 UniProt Comments for YWHAZ    14-3-3 zeta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Phosphorylation apparently disrupts homodimerization.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8q23.1

Cellular Component: extracellular space; protein complex; cytoplasmic vesicle membrane; mast cell granule; focal adhesion; mitochondrion; leading edge; postsynaptic density; cytosol; nucleoplasm; perinuclear region of cytoplasm; cytoplasm; melanosome; nucleus

Molecular Function: identical protein binding; protein domain specific binding; protein binding; protein complex binding; protein kinase binding; transcription factor binding

Biological Process: response to drug; platelet activation; histamine secretion by mast cell; apoptosis; establishment of Golgi localization; gene expression; blood coagulation; signal transduction; protein targeting to mitochondrion; negative regulation of apoptosis
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 Research Articles on YWHAZ    1. Overexpression of YWHAZ relates to tumor cell proliferation and malignant outcome of gastric carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-YWHAZ antibodyPathways associated with anti-YWHAZ antibody
 Reference Product  PubMed Publications
 TUBB antibody  >4 publications with YWHAZ and TUBB
 YWHAE antibody  >3 publications with YWHAZ and YWHAE
 BCR antibody  >2 publications with YWHAZ and BCR
 VIM antibody  >2 publications with YWHAZ and VIM
 LIMK1 antibody  >1 publications with YWHAZ and LIMK1
 IRS1 antibody  >1 publications with YWHAZ and IRS1
 FOXO3 antibody  >1 publications with YWHAZ and FOXO3
 EGFR antibody  >1 publications with YWHAZ and EGFR
 CFL1 antibody  >1 publications with YWHAZ and CFL1
 ABL1 antibody  >1 publications with YWHAZ and ABL1
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Class I PI3K Signaling Events Mediated By Akt Pathway antibodies  Class I PI3K Signaling Events Mediated By Akt Pathway Diagram
Diseases associated with anti-YWHAZ antibodyOrgans/Tissues associated with anti-YWHAZ antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >28 publications with YWHAZ and Neoplasms
 Carcinoma Antibodies  >12 publications with YWHAZ and Carcinoma
 Brain Diseases Antibodies  >10 publications with YWHAZ and Brain Diseases
 Nervous System Diseases Antibodies  >9 publications with YWHAZ and Nervous System Diseases
 Breast Neoplasms Antibodies  >7 publications with YWHAZ and Breast Neoplasms
 Skin Diseases Antibodies  >7 publications with YWHAZ and Skin Diseases
 Cardiovascular Diseases Antibodies  >6 publications with YWHAZ and Cardiovascular Diseases
 Inflammation Antibodies  >5 publications with YWHAZ and Inflammation
 Heart Diseases Antibodies  >4 publications with YWHAZ and Heart Diseases
 Drug Toxicity Antibodies  >3 publications with YWHAZ and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21 publications with YWHAZ and Brain
 Blood Antibodies  >18 publications with YWHAZ and Blood
 Liver Antibodies  >13 publications with YWHAZ and Liver
 Muscle Antibodies  >10 publications with YWHAZ and Muscle
 Heart Antibodies  >8 publications with YWHAZ and Heart
 Lung Antibodies  >6 publications with YWHAZ and Lung
 Kidney Antibodies  >5 publications with YWHAZ and Kidney
 Prostate Antibodies  >4 publications with YWHAZ and Prostate
 Stomach Antibodies  >4 publications with YWHAZ and Stomach
 Embryonic Tissue Antibodies  >4 publications with YWHAZ and Embryonic Tissue
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