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anti-14-3-3 zeta antibody :: 14-3-3 zeta Antibody

Scan QR to view Datasheet Catalog #    MBS852204
Western Blot (WB)
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3 zeta, Antibody

 Also Known As   

14-3-3 zeta Antibody

 Product Synonym Names    14-3-3 protein zeta/delta; 1433Z; 143Z; FAS; Factor activating exoenzyme S; KCIP-1,mitochondrial import stimulation factor S1 subunit; Protein kinase C inhibitor protein-1; YWHAZ
 Product Gene Name   

anti-14-3-3 zeta antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601288
 3D Structure    ModBase 3D Structure for P63104
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    14-3-3 zeta antibody detects endogenous levels of total 14-3-3 zeta protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human 14-3-3 zeta.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-14-3-3 zeta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-14-3-3 zeta antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-14-3-3 zeta antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-14-3-3 zeta antibody    WB: 1:500-1:1000
ELISA: 1:1000
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 Western Blot (WB) of anti-14-3-3 zeta antibody    Western blot analysis of extracts from HeLa cells, Jurkat cells and COLO cells, using 14-3-3 zeta antibody.
anti-14-3-3 zeta antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for 14-3-3 zeta. It may not necessarily be applicable to this product.
 NCBI GI #    208973238
 NCBI GeneID    7534
 NCBI Accession #    NP_001129171.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001135699.1 [Other Products]
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 UniProt Primary Accession #    P63104 [Other Products]
 UniProt Secondary Accession #    P29213; P29312; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33; A8K1N0; B7Z465 [Other Products]
 UniProt Related Accession #    P63104 [Other Products]
 Molecular Weight    19,333 Da
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 NCBI Official Full Name    14-3-3 protein zeta/delta
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
 NCBI Official Symbol    YWHAZ [Similar Products]
 NCBI Official Synonym Symbols   
HEL4; YWHAD; KCIP-1; HEL-S-3; HEL-S-93; 14-3-3-zeta
[Similar Products]
 NCBI Protein Information    14-3-3 protein zeta/delta
 UniProt Protein Name    14-3-3 protein zeta/delta
 UniProt Synonym Protein Names   
Protein kinase C inhibitor protein 1; KCIP-1
 UniProt Gene Name    YWHAZ [Similar Products]
 UniProt Synonym Gene Names    KCIP-1 [Similar Products]
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 NCBI Summary for 14-3-3 zeta    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]
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 UniProt Comments for 14-3-3 zeta    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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Product References and Citations for anti-14-3-3 zeta antibody

   Zupan L.A., J. Biol. Chem. 267:8707-8710(1992). Seluja G.A., Biochim. Biophys. Acta 1395:281-287(1998). Gevaert K., Nat. Biotechnol. 21:566-569(2003).
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 Research Articles on 14-3-3 zeta    1. Dimerization of 14-3-3 zeta (14-3-3zeta) dimer was disrupted by a double mutant (L12E, M78K).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-14-3-3 zeta antibodyPathways associated with anti-14-3-3 zeta antibody
 Reference Product  PubMed Publications
 TUBB antibody  >4 publications with 14-3-3 zeta and TUBB
 YWHAE antibody  >3 publications with 14-3-3 zeta and YWHAE
 BCR antibody  >2 publications with 14-3-3 zeta and BCR
 VIM antibody  >2 publications with 14-3-3 zeta and VIM
 LIMK1 antibody  >1 publications with 14-3-3 zeta and LIMK1
 IRS1 antibody  >1 publications with 14-3-3 zeta and IRS1
 FOXO3 antibody  >1 publications with 14-3-3 zeta and FOXO3
 EGFR antibody  >1 publications with 14-3-3 zeta and EGFR
 CFL1 antibody  >1 publications with 14-3-3 zeta and CFL1
 ABL1 antibody  >1 publications with 14-3-3 zeta and ABL1
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Class I PI3K Signaling Events Mediated By Akt Pathway antibodies  Class I PI3K Signaling Events Mediated By Akt Pathway Diagram
Diseases associated with anti-14-3-3 zeta antibodyOrgans/Tissues associated with anti-14-3-3 zeta antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >28 publications with 14-3-3 zeta and Neoplasms
 Carcinoma Antibodies  >12 publications with 14-3-3 zeta and Carcinoma
 Brain Diseases Antibodies  >10 publications with 14-3-3 zeta and Brain Diseases
 Nervous System Diseases Antibodies  >9 publications with 14-3-3 zeta and Nervous System Diseases
 Breast Neoplasms Antibodies  >7 publications with 14-3-3 zeta and Breast Neoplasms
 Skin Diseases Antibodies  >7 publications with 14-3-3 zeta and Skin Diseases
 Cardiovascular Diseases Antibodies  >6 publications with 14-3-3 zeta and Cardiovascular Diseases
 Inflammation Antibodies  >5 publications with 14-3-3 zeta and Inflammation
 Heart Diseases Antibodies  >4 publications with 14-3-3 zeta and Heart Diseases
 Drug Toxicity Antibodies  >3 publications with 14-3-3 zeta and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21 publications with 14-3-3 zeta and Brain
 Blood Antibodies  >18 publications with 14-3-3 zeta and Blood
 Liver Antibodies  >13 publications with 14-3-3 zeta and Liver
 Muscle Antibodies  >10 publications with 14-3-3 zeta and Muscle
 Heart Antibodies  >8 publications with 14-3-3 zeta and Heart
 Lung Antibodies  >6 publications with 14-3-3 zeta and Lung
 Kidney Antibodies  >5 publications with 14-3-3 zeta and Kidney
 Prostate Antibodies  >4 publications with 14-3-3 zeta and Prostate
 Stomach Antibodies  >4 publications with 14-3-3 zeta and Stomach
 Embryonic Tissue Antibodies  >4 publications with 14-3-3 zeta and Embryonic Tissue
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