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anti-5-HT-1A antibody :: 5-HT-1A Antibody

Scan QR to view Datasheet Catalog #    MBS858295
Western Blot (WB)
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

5-HT-1A, Antibody

 Also Known As   

5-HT-1A Antibody

 Product Synonym Names    5-HT1A; 5-hydroxytryptamine 1A receptor; 5HT1A; G-21; HTR1A; Serotonin receptor 1A
 Product Gene Name   

anti-5-HT-1A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    109760
 3D Structure    ModBase 3D Structure for P08908
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    5-HT-1A antibody detects endogenous levels of total 5-HT-1A protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human 5-HT-1A.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-5-HT-1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-5-HT-1A antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-5-HT-1A antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-5-HT-1A antibody    WB: 1:500~1:1000
ELISA: 1:20000
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 Western Blot (WB) of anti-5-HT-1A antibody    Western blot analysis of extracts from HepG2 cells and Jurkat cells, using 5-HT-1A antibody.
anti-5-HT-1A antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for 5-HT-1A. It may not necessarily be applicable to this product.
 NCBI GI #    55956923
 NCBI GeneID    3350
 NCBI Accession #    NP_000515.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000524.3 [Other Products]
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 UniProt Primary Accession #    P08908 [Other Products]
 UniProt Secondary Accession #    Q6LAE7 [Other Products]
 UniProt Related Accession #    P08908 [Other Products]
 Molecular Weight    46,107 Da
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 NCBI Official Full Name    5-hydroxytryptamine receptor 1A
 NCBI Official Synonym Full Names    5-hydroxytryptamine receptor 1A
 NCBI Official Symbol    HTR1A [Similar Products]
 NCBI Official Synonym Symbols   
G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1
[Similar Products]
 NCBI Protein Information    5-hydroxytryptamine receptor 1A
 UniProt Protein Name    5-hydroxytryptamine receptor 1A
 UniProt Synonym Protein Names   
G-21; Serotonin receptor 1A
 UniProt Gene Name    HTR1A [Similar Products]
 UniProt Synonym Gene Names    ADRB2RL1; ADRBRL1; 5-HT-1A; 5-HT1A [Similar Products]
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 NCBI Summary for 5-HT-1A    This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
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 UniProt Comments for 5-HT-1A    G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
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Product References and Citations for anti-5-HT-1A antibody

   Kobilka B.K., Nature 329:75-79(1987). The MGC Project Team, Genome Res. 14:2121-2127(2004). Parks C.L., Nucleic Acids Res. 19:7155-7160(1991).
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 Research Articles on 5-HT-1A    1. It is unlikely that the investigated genetic variants are clinically relevantly associated with depression after diagnosis of cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-5-HT-1A antibodyPathways associated with anti-5-HT-1A antibody
 Reference Product  PubMed Publications
 HTR1B antibody  >26 publications with 5-HT-1A and HTR1B
 HTR1D antibody  >9 publications with 5-HT-1A and HTR1D
 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Monoamine GPCRs Pathway antibodies  Monoamine GPCRs Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
Diseases associated with anti-5-HT-1A antibodyOrgans/Tissues associated with anti-5-HT-1A antibody
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >69 publications with 5-HT-1A and Mental Disorders
 Mood Disorders Antibodies  >42 publications with 5-HT-1A and Mood Disorders
 Depressive Disorder Antibodies  >34 publications with 5-HT-1A and Depressive Disorder
 Depressive Disorder, Major Antibodies  >30 publications with 5-HT-1A and Depressive Disorder, Major
 Anxiety Disorders Antibodies  >19 publications with 5-HT-1A and Anxiety Disorders
 Panic Disorder Antibodies  >6 publications with 5-HT-1A and Panic Disorder
 Bipolar Disorder Antibodies  >6 publications with 5-HT-1A and Bipolar Disorder
 Personality Disorders Antibodies  >6 publications with 5-HT-1A and Personality Disorders
 Cognition Disorders Antibodies  >3 publications with 5-HT-1A and Cognition Disorders
 Pain Antibodies  >3 publications with 5-HT-1A and Pain
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >51 publications with 5-HT-1A and Brain
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