NP_000856.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,682 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1E
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
NCBI Official Synonym Symbols
NCBI Protein Information
5-hydroxytryptamine receptor 1E; S31; 5-HT-1E; serotonin receptor 1E
UniProt Protein Name
5-hydroxytryptamine receptor 1E
UniProt Synonym Protein Names
S31; Serotonin receptor 1E
UniProt Synonym Gene Names
UniProt Entry Name
5HT1E_HUMAN
UniProt Comments for 5-HT-1E
5-HT(1E): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 6q14-q15
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; serotonin binding; serotonin receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cAMP metabolic process; G-protein signaling, adenylate cyclase inhibiting pathway; serotonin receptor signaling pathway
Research Articles on 5-HT-1E
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Pathways associated with anti-5-HT-1E antibody
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