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anti-5-HT-4 antibody :: 5-HT-4 Antibody

Scan QR to view Datasheet Catalog #    MBS854921
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

5-HT-4, Antibody

 Also Known As   

5-HT-4 Antibody

 Product Synonym Names    5-hydroxytryptamine receptor 4; 5-HT-4; Serotonin receptor 4; 5-HT4; HTR4
 Product Gene Name   

anti-5-HT-4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602164
 3D Structure    ModBase 3D Structure for Q13639
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    5-HT-4 antibody detects endogenous levels of total 5-HT-4 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human 5-HT-4.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-5-HT-4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-5-HT-4 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-5-HT-4 antibody   

Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-5-HT-4 antibody    WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:5000
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 Testing Data of anti-5-HT-4 antibody    anti-5-HT-4 antibody Testing Data image
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 Western Blot (WB) of anti-5-HT-4 antibody    Peptide-+ Western blot analysis of extracts from 293 cells, treated with insulin (0.01U/ml, 15mins), using 5-HT-4 antibody. Immunofluorescence analysis of HeLa cells, using 5-HT-4 antibody.
anti-5-HT-4 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for 5-HT-4. It may not necessarily be applicable to this product.
 NCBI GI #    11321563
 NCBI GeneID    3360
 NCBI Accession #    NP_000861.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000870.6 [Other Products]
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 UniProt Primary Accession #    Q13639 [Other Products]
 UniProt Secondary Accession #    Q546Q1; Q684M0; Q712M9; Q96KH9; Q96KI0; Q9H199; Q9NY73; Q9UBM6; Q9UBT4; Q9UE22; C4WYH4 [Other Products]
 UniProt Related Accession #    Q13639 [Other Products]
 Molecular Weight    46,907 Da
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 NCBI Official Full Name    5-hydroxytryptamine receptor 4 isoform b
 NCBI Official Synonym Full Names    5-hydroxytryptamine receptor 4
 NCBI Official Symbol    HTR4 [Similar Products]
 NCBI Official Synonym Symbols   
5-HT4; 5-HT4R
[Similar Products]
 NCBI Protein Information    5-hydroxytryptamine receptor 4
 UniProt Protein Name    5-hydroxytryptamine receptor 4
 UniProt Synonym Protein Names   
Serotonin receptor 4
 UniProt Gene Name    HTR4 [Similar Products]
 UniProt Synonym Gene Names    5-HT-4; 5-HT4 [Similar Products]
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 NCBI Summary for 5-HT-4    This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
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 UniProt Comments for 5-HT-4    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
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Product References and Citations for anti-5-HT-4 antibody

   Blondel O., J. Neurochem. 70:2252-2261(1998). Claeysen S., NeuroReport 8:3189-3195(1997). Claeysen S., Mol. Pharmacol. 55:910-920(1999).
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 Research Articles on 5-HT-4    1. found that testosterone, but not estradiol, correlated negatively with global 5-HT4R levels suggesting that men with high levels of testosterone have higher cerebral serotonergic tonus.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-5-HT-4 antibodyPathways associated with anti-5-HT-4 antibody
 Reference Product  PubMed Publications
 ADRB2 antibody  >1 publications with 5-HT-4 and ADRB2
 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Monoamine GPCRs Pathway antibodies  Monoamine GPCRs Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-5-HT-4 antibodyOrgans/Tissues associated with anti-5-HT-4 antibody
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >11 publications with 5-HT-4 and Mental Disorders
 Schizophrenia Antibodies  >7 publications with 5-HT-4 and Schizophrenia
 Mood Disorders Antibodies  >5 publications with 5-HT-4 and Mood Disorders
 Nervous System Diseases Antibodies  >3 publications with 5-HT-4 and Nervous System Diseases
 Disease Models, Animal Antibodies  >2 publications with 5-HT-4 and Disease Models, Animal
 Depressive Disorder Antibodies  >1 publications with 5-HT-4 and Depressive Disorder
 Gastroparesis Antibodies  >1 publications with 5-HT-4 and Gastroparesis
 Heart Diseases Antibodies  >1 publications with 5-HT-4 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with 5-HT-4 and Brain
 Intestine Antibodies  >3 publications with 5-HT-4 and Intestine
 Nerve Antibodies  >2 publications with 5-HT-4 and Nerve
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