Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ABCA6  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Solute Carrier Family 7, SCL7A5 (SLC12A7) Antibody
 • G Protein-Coupled Receptor Kinase 5 (GRK5) ELISA Kit
 • Envelope glycoprotein I (gI) Recombinant Protein
 • Complement C1q-like protein 3 (C1QL3) ELISA Kit
 • cyclooxygenase-2 (COX-2) ELISA Kit
 • Caspase 12 (CASPASE-12) ELISA Kit
 • Small toxic protein ibsC (ibsC) Recombinant Protein
 • CBLL1 Antibody
 • Anti Type II Collagen AutoAntibody (CII) ELISA Kit
 • cystathionine beta synthase (CBS) ELISA Kit
 • CD71 Antibody
 • Haptoglobin (HP) Native Protein
 • Alkaline Phosphatase (ALP) ELISA Kit
 • Beta-galactosidase (Glb1) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ABCA6 antibody :: anti-Human ABCA6 Antibody

Scan QR to view Datasheet Catalog #    MBS857956
Testing Data
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCA6, Antibody

 Also Known As   

ABCA6 Antibody

 Product Synonym Names    ABC transporter ABCA6; ABCA6; ATP-binding cassette A6; ATP-binding cassette sub-family A member 6; ATP-binding cassette, sub-family A (ABC1), member 6; EST155051; FLJ43498
 Product Gene Name   

anti-ABCA6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    131440
 3D Structure    ModBase 3D Structure for P09619
Section Bar
 Species Reactivity    Human
Section Bar
 Specificity    ABCA6 antibody detects endogenous levels of total ABCA6 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Section Bar
 Immunogen    The antiserum was produced against synthesized peptide derived from C-terminal of humanABCA6.
 All Sites    Human: Tyr771
Rat: Tyr770
Section Bar
 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-ABCA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-ABCA6 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-ABCA6 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-ABCA6 antibody    WB: 1:500~1:1000
ELISA: 1:40000
Section Bar
 Testing Data of anti-ABCA6 antibody    anti-ABCA6 antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ABCA6. It may not necessarily be applicable to this product.
 NCBI GI #    4505683
 NCBI GeneID    5159
 NCBI Accession #    NP_002600.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002609.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P09619 [Other Products]
 UniProt Secondary Accession #    Q8N5L4; B5A957 [Other Products]
 UniProt Related Accession #    P09619 [Other Products]
 Molecular Weight    37,412 Da
Table BarTOPTable Bar
 NCBI Official Full Name    platelet-derived growth factor receptor beta isoform 1
 NCBI Official Synonym Full Names    platelet derived growth factor receptor beta
 NCBI Official Symbol    PDGFRB [Similar Products]
 NCBI Official Synonym Symbols   
IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1
[Similar Products]
 NCBI Protein Information    platelet-derived growth factor receptor beta
 UniProt Protein Name    Platelet-derived growth factor receptor beta
 UniProt Synonym Protein Names   
Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; PDGFR-1; CD_antigen: CD140b
 Protein Family    ABC transporter A family
 UniProt Gene Name    PDGFRB [Similar Products]
 UniProt Synonym Gene Names    PDGFR; PDGFR1; PDGF-R-beta; PDGFR-beta; PDGFR-1 [Similar Products]
Section Bar
 NCBI Summary for ABCA6    The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Section Bar
 UniProt Comments for ABCA6    Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. Required for normal development of the cardiovascular system. Required for normal recruitment of pericytes (mesangial cells) in the kidney glomerulus, and for normal formation of a branched network of capillaries in kidney glomeruli. Promotes rearrangement of the actin cytoskeleton and the formation of membrane ruffles. Binding of its cognate ligands - homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFD -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PLCG1, PIK3R1, PTPN11, RASA1/GAP, CBL, SHC1 and NCK1. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca2+ and the activation of protein kinase C. Phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leads to the activation of the AKT1 signaling pathway. Phosphorylation of SHC1, or of the C-terminus of PTPN11, creates a binding site for GRB2, resulting in the activation of HRAS, RAF1 and down-stream MAP kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation and activation of SRC family kinases. Promotes phosphorylation of PDCD6IP/ALIX and STAM. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor.
Table BarTOPTable Bar
 

Product References and Citations for anti-ABCA6 antibody

   Kaminski W.E., Biochem. Biophys. Res. Commun. 285:1295-1301(2001). Arnould I., GeneScreen 1:157-164(2001). Ota T., Nat. Genet. 36:40-45(2004).
Section Bar
 Research Articles on ABCA6    1. These findings indicated that miR-518b may function as a tumor suppressor by targeting PDGFRB in the occurrence and development of GBM.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-ABCA6 antibodyPathways associated with anti-ABCA6 antibody
 Reference Product  PubMed Publications
 PDGFRA antibody  >1533 publications with ABCA6 and PDGFRA
 PDGFB antibody  >636 publications with ABCA6 and PDGFB
 SRC antibody  >216 publications with ABCA6 and SRC
 EGFR antibody  >133 publications with ABCA6 and EGFR
 JAK2 antibody  >43 publications with ABCA6 and JAK2
 PDGFD antibody  >32 publications with ABCA6 and PDGFD
 STAT3 antibody  >30 publications with ABCA6 and STAT3
 PTPN11 antibody  >29 publications with ABCA6 and PTPN11
 GRB2 antibody  >26 publications with ABCA6 and GRB2
 STAT1 antibody  >24 publications with ABCA6 and STAT1
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
Diseases associated with anti-ABCA6 antibodyOrgans/Tissues associated with anti-ABCA6 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1049 publications with ABCA6 and Neoplasms
 Fibrosis Antibodies  >302 publications with ABCA6 and Fibrosis
 Cardiovascular Diseases Antibodies  >248 publications with ABCA6 and Cardiovascular Diseases
 Brain Diseases Antibodies  >160 publications with ABCA6 and Brain Diseases
 Necrosis Antibodies  >143 publications with ABCA6 and Necrosis
 Kidney Diseases Antibodies  >141 publications with ABCA6 and Kidney Diseases
 Lung Diseases Antibodies  >140 publications with ABCA6 and Lung Diseases
 Inflammation Antibodies  >137 publications with ABCA6 and Inflammation
 Liver Diseases Antibodies  >135 publications with ABCA6 and Liver Diseases
 Hypertension Antibodies  >109 publications with ABCA6 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1180 publications with ABCA6 and Vascular
 Muscle Antibodies  >852 publications with ABCA6 and Muscle
 Blood Antibodies  >675 publications with ABCA6 and Blood
 Kidney Antibodies  >293 publications with ABCA6 and Kidney
 Lung Antibodies  >268 publications with ABCA6 and Lung
 Liver Antibodies  >250 publications with ABCA6 and Liver
 Bone Antibodies  >248 publications with ABCA6 and Bone
 Brain Antibodies  >244 publications with ABCA6 and Brain
 Embryonic Tissue Antibodies  >221 publications with ABCA6 and Embryonic Tissue
 Skin Antibodies  >163 publications with ABCA6 and Skin
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions